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Polymyxin Triple Combinations against Polymyxin-Resistant, Multidrug-Resistant, KPC-Producing Klebsiella pneumoniae.
Aye SM, Galani I, Yu H, Wang J, Chen K, Wickremasinghe H, Karaiskos I, Bergen PJ, Zhao J, Velkov T, Giamarellou H, Lin YW, Tsuji BT, Li J. Aye SM, et al. Among authors: wickremasinghe h. Antimicrob Agents Chemother. 2020 Jul 22;64(8):e00246-20. doi: 10.1128/AAC.00246-20. Print 2020 Jul 22. Antimicrob Agents Chemother. 2020. PMID: 32393492 Free PMC article.
Polymyxin B in Combination with Enrofloxacin Exerts Synergistic Killing against Extensively Drug-Resistant Pseudomonas aeruginosa.
Lin YW, Yu HH, Zhao J, Han ML, Zhu Y, Akter J, Wickremasinghe H, Walpola H, Wirth V, Rao GG, Forrest A, Velkov T, Li J. Lin YW, et al. Among authors: wickremasinghe h. Antimicrob Agents Chemother. 2018 May 25;62(6):e00028-18. doi: 10.1128/AAC.00028-18. Print 2018 Jun. Antimicrob Agents Chemother. 2018. PMID: 29632010 Free PMC article.
Novel Polymyxin Combination with the Antiretroviral Zidovudine Exerts Synergistic Killing against NDM-Producing Multidrug-Resistant Klebsiella pneumoniae.
Lin YW, Abdul Rahim N, Zhao J, Han ML, Yu HH, Wickremasinghe H, Chen K, Wang J, Paterson DL, Zhu Y, Rao GG, Zhou QT, Forrest A, Velkov T, Li J. Lin YW, et al. Among authors: wickremasinghe h. Antimicrob Agents Chemother. 2019 Mar 27;63(4):e02176-18. doi: 10.1128/AAC.02176-18. Print 2019 Apr. Antimicrob Agents Chemother. 2019. PMID: 30670431 Free PMC article.
Metabolic Perturbations Caused by the Over-Expression of mcr-1 in Escherichia coli.
Liu YY, Zhu Y, Wickremasinghe H, Bergen PJ, Lu J, Zhu XQ, Zhou QL, Azad M, Nang SC, Han ML, Lei T, Li J, Liu JH. Liu YY, et al. Among authors: wickremasinghe h. Front Microbiol. 2020 Oct 9;11:588658. doi: 10.3389/fmicb.2020.588658. eCollection 2020. Front Microbiol. 2020. PMID: 33162965 Free PMC article.
In vitro pharmacokinetics/pharmacodynamics of continuous ceftazidime infusion alone and in combination with colistin against Pseudomonas aeruginosa biofilm.
Gómez-Junyent J, Murillo O, Yu HH, Azad MAK, Wickremasinghe H, Rigo-Bonnin R, Benavent E, Ariza J, Li J. Gómez-Junyent J, et al. Among authors: wickremasinghe h. Int J Antimicrob Agents. 2021 Feb;57(2):106246. doi: 10.1016/j.ijantimicag.2020.106246. Epub 2020 Nov 28. Int J Antimicrob Agents. 2021. PMID: 33253904
A novel chemical biology and computational approach to expedite the discovery of new-generation polymyxins against life-threatening Acinetobacter baumannii.
Jiang X, Patil NA, Azad MAK, Wickremasinghe H, Yu H, Zhao J, Zhang X, Li M, Gong B, Wan L, Ma W, Thompson PE, Yang K, Yuan B, Schreiber F, Wang L, Velkov T, Roberts KD, Li J. Jiang X, et al. Among authors: wickremasinghe h. Chem Sci. 2021 Aug 19;12(36):12211-12220. doi: 10.1039/d1sc03460j. eCollection 2021 Sep 22. Chem Sci. 2021. PMID: 34667587 Free PMC article.
Comparative metabolomics revealed key pathways associated with the synergistic killing of multidrug-resistant Klebsiella pneumoniae by a bacteriophage-polymyxin combination.
Han ML, Nang SC, Lin YW, Zhu Y, Yu HH, Wickremasinghe H, Barlow CK, Creek DJ, Crawford S, Rao G, Dai C, Barr JJ, Chan K, Turner Schooley R, Velkov T, Li J. Han ML, et al. Among authors: wickremasinghe h. Comput Struct Biotechnol J. 2022 Jan 6;20:485-495. doi: 10.1016/j.csbj.2021.12.039. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 35070170 Free PMC article.
26 results