Osickova A - Search Results

1

Retargeting from the CR3 to the LFA-1 receptor uncovers the adenylyl cyclase enzyme-translocating segment of Bordetella adenylate cyclase toxin.

Masin J, Osickova A, Jurnecka D, Klimova N, Khaliq H, Sebo P, Osicka R. Masin J, et al. Among authors: osickova a. J Biol Chem. 2020 Jul 10;295(28):9349-9365. doi: 10.1074/jbc.RA120.013630. Epub 2020 May 11. J Biol Chem. 2020. PMID: 32393579 Free PMC article.

2

Delivery of CD8(+) T-cell epitopes into major histocompatibility complex class I antigen presentation pathway by Bordetella pertussis adenylate cyclase: delineation of cell invasive structures and permissive insertion sites.

Osicka R, Osicková A, Basar T, Guermonprez P, Rojas M, Leclerc C, Sebo P. Osicka R, et al. Among authors: osickova a. Infect Immun. 2000 Jan;68(1):247-56. doi: 10.1128/IAI.68.1.247-256.2000. Infect Immun. 2000. PMID: 10603395 Free PMC article.

3

An amphipathic alpha-helix including glutamates 509 and 516 is crucial for membrane translocation of adenylate cyclase toxin and modulates formation and cation selectivity of its membrane channels.

Osicková A, Osicka R, Maier E, Benz R, Sebo P. Osicková A, et al. J Biol Chem. 1999 Dec 31;274(53):37644-50. J Biol Chem. 1999. PMID: 10608820 Free article.

4

Delivery of multiple epitopes by recombinant detoxified adenylate cyclase of Bordetella pertussis induces protective antiviral immunity.

Fayolle C, Osickova A, Osicka R, Henry T, Rojas MJ, Saron MF, Sebo P, Leclerc C. Fayolle C, et al. Among authors: osickova a. J Virol. 2001 Aug;75(16):7330-8. doi: 10.1128/JVI.75.16.7330-7338.2001. J Virol. 2001. PMID: 11462005 Free PMC article.

5

Adenylate cyclase toxin translocates across target cell membrane without forming a pore.

Osickova A, Masin J, Fayolle C, Krusek J, Basler M, Pospisilova E, Leclerc C, Osicka R, Sebo P. Osickova A, et al. Mol Microbiol. 2010 Mar;75(6):1550-62. doi: 10.1111/j.1365-2958.2010.07077.x. Epub 2010 Feb 23. Mol Microbiol. 2010. PMID: 20199594 Free article.

6

Intrinsically disordered enamel matrix protein ameloblastin forms ribbon-like supramolecular structures via an N-terminal segment encoded by exon 5.

Wald T, Osickova A, Sulc M, Benada O, Semeradtova A, Rezabkova L, Veverka V, Bednarova L, Maly J, Macek P, Sebo P, Slaby I, Vondrasek J, Osicka R. Wald T, et al. Among authors: osickova a. J Biol Chem. 2013 Aug 2;288(31):22333-45. doi: 10.1074/jbc.M113.456012. Epub 2013 Jun 19. J Biol Chem. 2013. PMID: 23782691 Free PMC article.

7

Interaction of Bordetella adenylate cyclase toxin with complement receptor 3 involves multivalent glycan binding.

Hasan S, Osickova A, Bumba L, Novák P, Sebo P, Osicka R. Hasan S, et al. Among authors: osickova a. FEBS Lett. 2015 Jan 30;589(3):374-9. doi: 10.1016/j.febslet.2014.12.023. Epub 2014 Dec 29. FEBS Lett. 2015. PMID: 25554420 Free article.

8

Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3.

Osicka R, Osickova A, Hasan S, Bumba L, Cerny J, Sebo P. Osicka R, et al. Among authors: osickova a. Elife. 2015 Dec 9;4:e10766. doi: 10.7554/eLife.10766. Elife. 2015. PMID: 26650353 Free PMC article.

9

Transmembrane segments of complement receptor 3 do not participate in cytotoxic activities but determine receptor structure required for action of Bordetella adenylate cyclase toxin.

Wald T, Osickova A, Masin J, Liskova PM, Petry-Podgorska I, Matousek T, Sebo P, Osicka R. Wald T, et al. Among authors: osickova a. Pathog Dis. 2016 Apr;74(3):ftw008. doi: 10.1093/femspd/ftw008. Epub 2016 Jan 21. Pathog Dis. 2016. PMID: 26802078

10

Negatively charged residues of the segment linking the enzyme and cytolysin moieties restrict the membrane-permeabilizing capacity of adenylate cyclase toxin.

Masin J, Osickova A, Sukova A, Fiser R, Halada P, Bumba L, Linhartova I, Osicka R, Sebo P. Masin J, et al. Among authors: osickova a. Sci Rep. 2016 Sep 1;6:29137. doi: 10.1038/srep29137. Sci Rep. 2016. PMID: 27581058 Free PMC article.

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