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Page 1
The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis.
Carrat GR, Haythorne E, Tomas A, Haataja L, Müller A, Arvan P, Piunti A, Cheng K, Huang M, Pullen TJ, Georgiadou E, Stylianides T, Amirruddin NS, Salem V, Distaso W, Cakebread A, Heesom KJ, Lewis PA, Hodson DJ, Briant LJ, Fung ACH, Sessions RB, Alpy F, Kong APS, Benke PI, Torta F, Teo AKK, Leclerc I, Solimena M, Wigley DB, Rutter GA. Carrat GR, et al. Among authors: distaso w. Mol Metab. 2020 Oct;40:101015. doi: 10.1016/j.molmet.2020.101015. Epub 2020 May 13. Mol Metab. 2020. PMID: 32416313 Free PMC article.
Leader β-cells coordinate Ca2+ dynamics across pancreatic islets in vivo.
Salem V, Silva LD, Suba K, Georgiadou E, Neda Mousavy Gharavy S, Akhtar N, Martin-Alonso A, Gaboriau DCA, Rothery SM, Stylianides T, Carrat G, Pullen TJ, Singh SP, Hodson DJ, Leclerc I, Shapiro AMJ, Marchetti P, Briant LJB, Distaso W, Ninov N, Rutter GA. Salem V, et al. Among authors: distaso w. Nat Metab. 2019 Jun;1(6):615-629. doi: 10.1038/s42255-019-0075-2. Epub 2019 Jun 14. Nat Metab. 2019. PMID: 32694805
Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes.
de Jesus DS, Mak TCS, Wang YF, von Ohlen Y, Bai Y, Kane E, Chabosseau P, Chahrour CM, Distaso W, Salem V, Tomas A, Stoffel M, Rutter GA, Latreille M. de Jesus DS, et al. Among authors: distaso w. Mol Metab. 2021 Nov;53:101248. doi: 10.1016/j.molmet.2021.101248. Epub 2021 May 12. Mol Metab. 2021. PMID: 33989778 Free PMC article.
The benefit of dexamethasone in patients with COVID-19 infection is preserved in patients with diabetes.
Eng PC, Distaso W, Durreshahwar H, Shaikhali Y, Narendranathan D, Cassin-Scott R, Misra S, Hill NE, Tharakan G, Oliver NS, Tan TM, Izzi-Engbeaya C, Salem V. Eng PC, et al. Among authors: distaso w. Diabetes Obes Metab. 2022 Jul;24(7):1385-1389. doi: 10.1111/dom.14692. Epub 2022 Apr 3. Diabetes Obes Metab. 2022. PMID: 35293117 Free PMC article. No abstract available.
Adverse outcomes in COVID-19 and diabetes: a retrospective cohort study from three London teaching hospitals.
Izzi-Engbeaya C, Distaso W, Amin A, Yang W, Idowu O, Kenkre JS, Shah RJ, Woin E, Shi C, Alavi N, Bedri H, Brady N, Blackburn S, Leczycka M, Patel S, Sokol E, Toke-Bjolgerud E, Qayum A, Abdel-Malek M, Hope DCD, Oliver NS, Bravis V, Misra S, Tan TM, Hill NE, Salem V. Izzi-Engbeaya C, et al. Among authors: distaso w. BMJ Open Diabetes Res Care. 2021 Jan;9(1):e001858. doi: 10.1136/bmjdrc-2020-001858. BMJ Open Diabetes Res Care. 2021. PMID: 33408084 Free PMC article.
Intra-islet glucagon signalling regulates beta-cell connectivity, first-phase insulin secretion and glucose homoeostasis.
Suba K, Patel Y, Martin-Alonso A, Hansen B, Xu X, Roberts A, Norton M, Chung P, Shrewsbury J, Kwok R, Kalogianni V, Chen S, Liu X, Kalyviotis K, Rutter GA, Jones B, Minnion J, Owen BM, Pantazis P, Distaso W, Drucker DJ, Tan TM, Bloom SR, Murphy KG, Salem V. Suba K, et al. Among authors: distaso w. Mol Metab. 2024 Jul;85:101947. doi: 10.1016/j.molmet.2024.101947. Epub 2024 Apr 26. Mol Metab. 2024. PMID: 38677509 Free PMC article.
The vagus nerve mediates the physiological but not pharmacological effects of PYY3-36 on food intake.
Alonso AM, Cork SC, Phuah P, Hansen B, Norton M, Cheng S, Xu X, Suba K, Ma Y, Dowsett GK, Tadross JA, Lam BY, Yeo GS, Herzog H, Bloom SR, Arnold M, Distaso W, Murphy KG, Salem V. Alonso AM, et al. Among authors: distaso w. Mol Metab. 2024 Mar;81:101895. doi: 10.1016/j.molmet.2024.101895. Epub 2024 Feb 8. Mol Metab. 2024. PMID: 38340808 Free PMC article.
COVID-19: Tail risk and predictive regressions.
Distaso W, Ibragimov R, Semenov A, Skrobotov A. Distaso W, et al. PLoS One. 2022 Dec 1;17(12):e0275516. doi: 10.1371/journal.pone.0275516. eCollection 2022. PLoS One. 2022. PMID: 36454731 Free PMC article.