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Page 1
A novel proangiogenic B cell subset is increased in cancer and chronic inflammation.
van de Veen W, Globinska A, Jansen K, Straumann A, Kubo T, Verschoor D, Wirz OF, Castro-Giner F, Tan G, Rückert B, Ochsner U, Herrmann M, Stanić B, van Splunter M, Huntjens D, Wallimann A, Fonseca Guevara RJ, Spits H, Ignatova D, Chang YT, Fassnacht C, Guenova E, Flatz L, Akdis CA, Akdis M. van de Veen W, et al. Among authors: flatz l. Sci Adv. 2020 May 13;6(20):eaaz3559. doi: 10.1126/sciadv.aaz3559. eCollection 2020 May. Sci Adv. 2020. PMID: 32426497 Free PMC article.
Association of Checkpoint Inhibitor-Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non-Small Cell Lung Cancer.
Berner F, Bomze D, Diem S, Ali OH, Fässler M, Ring S, Niederer R, Ackermann CJ, Baumgaertner P, Pikor N, Cruz CG, van de Veen W, Akdis M, Nikolaev S, Läubli H, Zippelius A, Hartmann F, Cheng HW, Hönger G, Recher M, Goldman J, Cozzio A, Früh M, Neefjes J, Driessen C, Ludewig B, Hegazy AN, Jochum W, Speiser DE, Flatz L. Berner F, et al. Among authors: flatz l. JAMA Oncol. 2019 Jul 1;5(7):1043-1047. doi: 10.1001/jamaoncol.2019.0402. JAMA Oncol. 2019. PMID: 31021392 Free PMC article. Clinical Trial.
PTCH1 inactivation is sufficient to cause basaloid follicular hamartoma in paediatric Nevoid basal cell carcinoma syndrome.
Blanchard G, Yurchenko AA, Pop OT, Weibel L, Theiler M, Hauser V, Fraitag S, Guenova E, Flatz L, Nikolaev SI, Hohl D. Blanchard G, et al. Among authors: flatz l. J Eur Acad Dermatol Venereol. 2022 Nov;36(11):e954-e956. doi: 10.1111/jdv.18382. Epub 2022 Jul 8. J Eur Acad Dermatol Venereol. 2022. PMID: 35770464 No abstract available.
Immune signatures predict development of autoimmune toxicity in patients with cancer treated with immune checkpoint inhibitors.
Nuñez NG, Berner F, Friebel E, Unger S, Wyss N, Gomez JM, Purde MT, Niederer R, Porsch M, Lichtensteiger C, Kramer R, Erdmann M, Schmitt C, Heinzerling L, Abdou MT, Karbach J, Schadendorf D, Zimmer L, Ugurel S, Klümper N, Hölzel M, Power L, Kreutmair S, Capone M, Madonna G, Cevhertas L, Heider A, Amaral T, Hasan Ali O, Bomze D, Dimitriou F, Diem S, Ascierto PA, Dummer R, Jäger E, Driessen C, Levesque MP, van de Veen W, Joerger M, Früh M, Becher B, Flatz L. Nuñez NG, et al. Among authors: flatz l. Med. 2023 Feb 10;4(2):113-129.e7. doi: 10.1016/j.medj.2022.12.007. Epub 2023 Jan 23. Med. 2023. PMID: 36693381 Free article.
Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8+ T cells.
Cupovic J, Ring SS, Onder L, Colston JM, Lütge M, Cheng HW, De Martin A, Provine NM, Flatz L, Oxenius A, Scandella E, Krebs P, Engeler D, Klenerman P, Ludewig B. Cupovic J, et al. Among authors: flatz l. Nat Immunol. 2021 Aug;22(8):1042-1051. doi: 10.1038/s41590-021-00969-3. Epub 2021 Jul 15. Nat Immunol. 2021. PMID: 34267375 Free PMC article.
Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment.
Ring SS, Cupovic J, Onder L, Lütge M, Perez-Shibayama C, Gil-Cruz C, Scandella E, De Martin A, Mörbe U, Hartmann F, Wenger R, Spiegl M, Besse A, Bonilla WV, Stemeseder F, Schmidt S, Orlinger KK, Krebs P, Ludewig B, Flatz L. Ring SS, et al. Among authors: flatz l. Nat Commun. 2021 Aug 5;12(1):4734. doi: 10.1038/s41467-021-25057-w. Nat Commun. 2021. PMID: 34354077 Free PMC article.
Adoptive T Cell Therapy Targeting Different Gene Products Reveals Diverse and Context-Dependent Immune Evasion in Melanoma.
Effern M, Glodde N, Braun M, Liebing J, Boll HN, Yong M, Bawden E, Hinze D, van den Boorn-Konijnenberg D, Daoud M, Aymans P, Landsberg J, Smyth MJ, Flatz L, Tüting T, Bald T, Gebhardt T, Hölzel M. Effern M, et al. Among authors: flatz l. Immunity. 2020 Sep 15;53(3):564-580.e9. doi: 10.1016/j.immuni.2020.07.007. Epub 2020 Aug 3. Immunity. 2020. PMID: 32750334 Free article.
Molecular, clinicopathological, and immune correlates of LAG3 promoter DNA methylation in melanoma.
Fröhlich A, Sirokay J, Fietz S, Vogt TJ, Dietrich J, Zarbl R, Florin M, Kuster P, Saavedra G, Valladolid SR, Hoffmann F, Flatz L, Ring SS, Golletz C, Pietsch T, Strieth S, Brossart P, Gielen GH, Kristiansen G, Bootz F, Landsberg J, Dietrich D. Fröhlich A, et al. Among authors: flatz l. EBioMedicine. 2020 Sep;59:102962. doi: 10.1016/j.ebiom.2020.102962. Epub 2020 Aug 30. EBioMedicine. 2020. PMID: 32861198 Free PMC article.
Regulatory T Cells Restrain Pathogenic T Helper Cells during Skin Inflammation.
Hartwig T, Zwicky P, Schreiner B, Yawalkar N, Cheng P, Navarini A, Dummer R, Flatz L, Conrad C, Schlapbach C, Becher B. Hartwig T, et al. Among authors: flatz l. Cell Rep. 2018 Dec 26;25(13):3564-3572.e4. doi: 10.1016/j.celrep.2018.12.012. Cell Rep. 2018. PMID: 30590032 Free article.
131 results