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T cells with dysfunctional mitochondria induce multimorbidity and premature senescence.
Desdín-Micó G, Soto-Heredero G, Aranda JF, Oller J, Carrasco E, Gabandé-Rodríguez E, Blanco EM, Alfranca A, Cussó L, Desco M, Ibañez B, Gortazar AR, Fernández-Marcos P, Navarro MN, Hernaez B, Alcamí A, Baixauli F, Mittelbrunn M. Desdín-Micó G, et al. Among authors: soto heredero g. Science. 2020 Jun 19;368(6497):1371-1376. doi: 10.1126/science.aax0860. Epub 2020 May 21. Science. 2020. PMID: 32439659
Mitochondrial activity in T cells.
Desdín-Micó G, Soto-Heredero G, Mittelbrunn M. Desdín-Micó G, et al. Among authors: soto heredero g. Mitochondrion. 2018 Jul;41:51-57. doi: 10.1016/j.mito.2017.10.006. Epub 2017 Oct 12. Mitochondrion. 2018. PMID: 29032101 Free article. Review.
Glycolysis - a key player in the inflammatory response.
Soto-Heredero G, Gómez de Las Heras MM, Gabandé-Rodríguez E, Oller J, Mittelbrunn M. Soto-Heredero G, et al. FEBS J. 2020 Aug;287(16):3350-3369. doi: 10.1111/febs.15327. Epub 2020 Apr 27. FEBS J. 2020. PMID: 32255251 Free PMC article. Review.
Mitochondrial dysfunction defines T cell exhaustion.
Soto-Heredero G, Desdín-Micó G, Mittelbrunn M. Soto-Heredero G, et al. Cell Metab. 2021 Mar 2;33(3):470-472. doi: 10.1016/j.cmet.2021.02.010. Cell Metab. 2021. PMID: 33657392 Free article.