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The PSEN1 E280G mutation leads to increased amyloid-β43 production in induced pluripotent stem cell neurons and deposition in brain tissue.
Willumsen N, Arber C, Lovejoy C, Toombs J, Alatza A, Weston PSJ, Chávez-Gutiérrez L, Hardy J, Zetterberg H, Fox NC, Ryan NS, Lashley T, Wray S. Willumsen N, et al. Among authors: lovejoy c. Brain Commun. 2022 Dec 7;5(1):fcac321. doi: 10.1093/braincomms/fcac321. eCollection 2023. Brain Commun. 2022. PMID: 36687397 Free PMC article.
Familial Alzheimer's disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta.
Arber C, Toombs J, Lovejoy C, Ryan NS, Paterson RW, Willumsen N, Gkanatsiou E, Portelius E, Blennow K, Heslegrave A, Schott JM, Hardy J, Lashley T, Fox NC, Zetterberg H, Wray S. Arber C, et al. Among authors: lovejoy c. Mol Psychiatry. 2020 Nov;25(11):2919-2931. doi: 10.1038/s41380-019-0410-8. Epub 2019 Apr 12. Mol Psychiatry. 2020. PMID: 30980041 Free PMC article.
Age-related changes in the energy of human mesenchymal stem cells.
Barilani M, Lovejoy C, Piras R, Abramov AY, Lazzari L, Angelova PR. Barilani M, et al. Among authors: lovejoy c. J Cell Physiol. 2022 Mar;237(3):1753-1767. doi: 10.1002/jcp.30638. Epub 2021 Nov 17. J Cell Physiol. 2022. PMID: 34791648
Vulnerability of Arctic Ocean microbial eukaryotes to sea ice loss.
Jackson VLN, Grevesse T, Kilias ES, Onda DFL, Young KF, Allen MJ, Walsh DA, Lovejoy C, Monier A. Jackson VLN, et al. Among authors: lovejoy c. Sci Rep. 2024 Nov 21;14(1):28896. doi: 10.1038/s41598-024-77821-9. Sci Rep. 2024. PMID: 39572565 Free PMC article.
242 results