Huse JT - Search Results

1

Targeting therapeutic vulnerabilities with PARP inhibition and radiation in IDH-mutant gliomas and cholangiocarcinomas.

Wang Y, Wild AT, Turcan S, Wu WH, Sigel C, Klimstra DS, Ma X, Gong Y, Holland EC, Huse JT, Chan TA. Wang Y, et al. Among authors: huse jt. Sci Adv. 2020 Apr 22;6(17):eaaz3221. doi: 10.1126/sciadv.aaz3221. eCollection 2020 Apr. Sci Adv. 2020. PMID: 32494639 Free PMC article.

2

Genetically engineered mouse models of brain cancer and the promise of preclinical testing.

Huse JT, Holland EC. Huse JT, et al. Brain Pathol. 2009 Jan;19(1):132-43. doi: 10.1111/j.1750-3639.2008.00234.x. Brain Pathol. 2009. PMID: 19076778 Free PMC article. Review.

3

PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells.

Bleau AM, Hambardzumyan D, Ozawa T, Fomchenko EI, Huse JT, Brennan CW, Holland EC. Bleau AM, et al. Among authors: huse jt. Cell Stem Cell. 2009 Mar 6;4(3):226-35. doi: 10.1016/j.stem.2009.01.007. Cell Stem Cell. 2009. PMID: 19265662 Free PMC article.

4

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo.

Huse JT, Brennan C, Hambardzumyan D, Wee B, Pena J, Rouhanifard SH, Sohn-Lee C, le Sage C, Agami R, Tuschl T, Holland EC. Huse JT, et al. Genes Dev. 2009 Jun 1;23(11):1327-37. doi: 10.1101/gad.1777409. Genes Dev. 2009. PMID: 19487573 Free PMC article.

5

The ABCG2 resistance network of glioblastoma.

Bleau AM, Huse JT, Holland EC. Bleau AM, et al. Among authors: huse jt. Cell Cycle. 2009 Sep 15;8(18):2936-44. Epub 2009 Sep 13. Cell Cycle. 2009. PMID: 19713741 Review.

6

Yin and yang: cancer-implicated miRNAs that have it both ways.

Huse JT, Holland EC. Huse JT, et al. Cell Cycle. 2009 Nov 15;8(22):3611-2. doi: 10.4161/cc.8.22.9893. Cell Cycle. 2009. PMID: 19855181 No abstract available.

7

Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma.

Becher OJ, Hambardzumyan D, Walker TR, Helmy K, Nazarian J, Albrecht S, Hiner RL, Gall S, Huse JT, Jabado N, MacDonald TJ, Holland EC. Becher OJ, et al. Among authors: huse jt. Cancer Res. 2010 Mar 15;70(6):2548-57. doi: 10.1158/0008-5472.CAN-09-2503. Epub 2010 Mar 2. Cancer Res. 2010. PMID: 20197468 Free PMC article.

8

Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma.

Huse JT, Holland EC. Huse JT, et al. Nat Rev Cancer. 2010 May;10(5):319-31. doi: 10.1038/nrc2818. Nat Rev Cancer. 2010. PMID: 20414201 Review.

9

PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas.

Ozawa T, Brennan CW, Wang L, Squatrito M, Sasayama T, Nakada M, Huse JT, Pedraza A, Utsuki S, Yasui Y, Tandon A, Fomchenko EI, Oka H, Levine RL, Fujii K, Ladanyi M, Holland EC. Ozawa T, et al. Among authors: huse jt. Genes Dev. 2010 Oct 1;24(19):2205-18. doi: 10.1101/gad.1972310. Genes Dev. 2010. PMID: 20889717 Free PMC article.

10

Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas.

Squatrito M, Brennan CW, Helmy K, Huse JT, Petrini JH, Holland EC. Squatrito M, et al. Among authors: huse jt. Cancer Cell. 2010 Dec 14;18(6):619-29. doi: 10.1016/j.ccr.2010.10.034. Cancer Cell. 2010. PMID: 21156285 Free PMC article.

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