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Page 1
An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development.
Shankar S, Tien JC, Siebenaler RF, Chugh S, Dommeti VL, Zelenka-Wang S, Wang XM, Apel IJ, Waninger J, Eyunni S, Xu A, Mody M, Goodrum A, Zhang Y, Tesmer JJ, Mannan R, Cao X, Vats P, Pitchiaya S, Ellison SJ, Shi J, Kumar-Sinha C, Crawford HC, Chinnaiyan AM. Shankar S, et al. Among authors: waninger j. Nat Commun. 2020 Jun 4;11(1):2817. doi: 10.1038/s41467-020-16309-2. Nat Commun. 2020. PMID: 32499547 Free PMC article.
Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination.
Yu J, Green MD, Li S, Sun Y, Journey SN, Choi JE, Rizvi SM, Qin A, Waninger JJ, Lang X, Chopra Z, El Naqa I, Zhou J, Bian Y, Jiang L, Tezel A, Skvarce J, Achar RK, Sitto M, Rosen BS, Su F, Narayanan SP, Cao X, Wei S, Szeliga W, Vatan L, Mayo C, Morgan MA, Schonewolf CA, Cuneo K, Kryczek I, Ma VT, Lao CD, Lawrence TS, Ramnath N, Wen F, Chinnaiyan AM, Cieslik M, Alva A, Zou W. Yu J, et al. Among authors: waninger jj. Nat Med. 2021 Jan;27(1):152-164. doi: 10.1038/s41591-020-1131-x. Epub 2021 Jan 4. Nat Med. 2021. PMID: 33398162 Free PMC article.
Biochemical characterization of the interaction between KRAS and Argonaute 2.
Waninger JJ, Beyett TS, Gadkari VV, Siebenaler RF, Kenum C, Shankar S, Ruotolo BT, Chinnaiyan AM, Tesmer JJG. Waninger JJ, et al. Biochem Biophys Rep. 2021 Dec 20;29:101191. doi: 10.1016/j.bbrep.2021.101191. eCollection 2022 Mar. Biochem Biophys Rep. 2021. PMID: 34988297 Free PMC article.
Argonaute 2 modulates EGFR-RAS signaling to promote mutant HRAS and NRAS-driven malignancies.
Siebenaler RF, Chugh S, Waninger JJ, Dommeti VL, Kenum C, Mody M, Gautam A, Patel N, Chu A, Bawa P, Hon J, Smith RD, Carlson H, Cao X, Tesmer JJG, Shankar S, Chinnaiyan AM. Siebenaler RF, et al. Among authors: waninger jj. PNAS Nexus. 2022 Jul 28;1(3):pgac084. doi: 10.1093/pnasnexus/pgac084. eCollection 2022 Jul. PNAS Nexus. 2022. PMID: 35923912 Free PMC article.
Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy.
Li G, Choi JE, Kryczek I, Sun Y, Liao P, Li S, Wei S, Grove S, Vatan L, Nelson R, Schaefer G, Allen SG, Sankar K, Fecher LA, Mendiratta-Lala M, Frankel TL, Qin A, Waninger JJ, Tezel A, Alva A, Lao CD, Ramnath N, Cieslik M, Harms PW, Green MD, Chinnaiyan AM, Zou W. Li G, et al. Among authors: waninger jj. Cancer Cell. 2023 Feb 13;41(2):304-322.e7. doi: 10.1016/j.ccell.2022.12.008. Epub 2023 Jan 12. Cancer Cell. 2023. PMID: 36638784 Free PMC article.
Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity.
Chow A, Schad S, Green MD, Hellmann MD, Allaj V, Ceglia N, Zago G, Shah NS, Sharma SK, Mattar M, Chan J, Rizvi H, Zhong H, Liu C, Bykov Y, Zamarin D, Shi H, Budhu S, Wohlhieter C, Uddin F, Gupta A, Khodos I, Waninger JJ, Qin A, Markowitz GJ, Mittal V, Balachandran V, Durham JN, Le DT, Zou W, Shah SP, McPherson A, Panageas K, Lewis JS, Perry JSA, de Stanchina E, Sen T, Poirier JT, Wolchok JD, Rudin CM, Merghoub T. Chow A, et al. Among authors: waninger jj. Cancer Cell. 2021 Jul 12;39(7):973-988.e9. doi: 10.1016/j.ccell.2021.05.006. Epub 2021 Jun 10. Cancer Cell. 2021. PMID: 34115989 Free PMC article.
The impact of BRAF mutation status on clinical outcomes with anti-PD-1 monotherapy versus combination ipilimumab/nivolumab in treatment-naïve advanced stage melanoma.
Ma VT, Daignault-Newton S, Waninger JJ, Journey S, Chopra Z, Tezel A, Redman BG, Fecher LA, Green MD, Alva AS, Lao CD. Ma VT, et al. Among authors: waninger jj. Pigment Cell Melanoma Res. 2021 May;34(3):629-640. doi: 10.1111/pcmr.12944. Epub 2020 Nov 22. Pigment Cell Melanoma Res. 2021. PMID: 33128316 Free article.
Validation of the American Joint Committee on Cancer Eighth Edition Staging of Patients With Metastatic Cutaneous Melanoma Treated With Immune Checkpoint Inhibitors.
Waninger JJ, Ma VT, Journey S, Skvarce J, Chopra Z, Tezel A, Bryant AK, Mayo C, Sun Y, Sankar K, Ramnath N, Lao C, Sussman JB, Fecher L, Alva A, Green MD. Waninger JJ, et al. JAMA Netw Open. 2021 Mar 1;4(3):e210980. doi: 10.1001/jamanetworkopen.2021.0980. JAMA Netw Open. 2021. PMID: 33687443 Free PMC article.
Bone Metastases, Skeletal-Related Events, and Survival in Patients With Metastatic Non-Small Cell Lung Cancer Treated With Immune Checkpoint Inhibitors.
Qin A, Zhao S, Miah A, Wei L, Patel S, Johns A, Grogan M, Bertino EM, He K, Shields PG, Kalemkerian GP, Gadgeel SM, Ramnath N, Schneider BJ, Hassan KA, Szerlip N, Chopra Z, Journey S, Waninger J, Spakowicz D, Carbone DP, Presley CJ, Otterson GA, Green MD, Owen DH. Qin A, et al. Among authors: waninger j. J Natl Compr Canc Netw. 2021 Apr 20;19(8):915-921. doi: 10.6004/jnccn.2020.7668. J Natl Compr Canc Netw. 2021. PMID: 33878726 Free PMC article.
59 results