Paula FR - Search Results

1

Synthesis of novel 3,5,6-trisubstituted 2-pyridone derivatives and evaluation for their anti-inflammatory activity.

Gonçalves DS, de S Melo SM, Jacomini AP, J V da Silva M, Pianoski KE, Ames FQ, Aguiar RP, Oliveira AF, Volpato H, Bidóia DL, Nakamura CV, Bersani-Amado CA, Back DF, Moura S, Paula FR, Rosa FA. Gonçalves DS, et al. Among authors: paula fr. Bioorg Med Chem. 2020 Jun 15;28(12):115549. doi: 10.1016/j.bmc.2020.115549. Epub 2020 May 12. Bioorg Med Chem. 2020. PMID: 32503692

2

Molecular modeling studies and in vitro bioactivity evaluation of a set of novel 5-nitro-heterocyclic derivatives as anti-T. cruzi agents.

Paula FR, Jorge SD, de Almeida LV, Pasqualoto KF, Tavares LC. Paula FR, et al. Bioorg Med Chem. 2009 Apr 1;17(7):2673-9. doi: 10.1016/j.bmc.2009.02.056. Epub 2009 Mar 5. Bioorg Med Chem. 2009. PMID: 19303308 Free article.

3

Synthesis and evaluation against Leishmania amazonensis of novel pyrazolo[3,4-d]pyridazinone-N-acylhydrazone-(bi)thiophene hybrids.

Jacomini AP, Silva MJV, Silva RGM, Gonçalves DS, Volpato H, Basso EA, Paula FR, Nakamura CV, Sarragiotto MH, Rosa FA. Jacomini AP, et al. Among authors: paula fr. Eur J Med Chem. 2016 Nov 29;124:340-349. doi: 10.1016/j.ejmech.2016.08.048. Epub 2016 Aug 23. Eur J Med Chem. 2016. PMID: 27597410

4

Synthesis and SAR of new isoxazole-triazole bis-heterocyclic compounds as analogues of natural lignans with antiparasitic activity.

Zimmermann LA, de Moraes MH, da Rosa R, de Melo EB, Paula FR, Schenkel EP, Steindel M, Bernardes LSC. Zimmermann LA, et al. Among authors: paula fr. Bioorg Med Chem. 2018 Sep 15;26(17):4850-4862. doi: 10.1016/j.bmc.2018.08.025. Epub 2018 Aug 19. Bioorg Med Chem. 2018. PMID: 30173929

5

Bio-guided search of active indole alkaloids from Tabernaemontana catharinensis: Antitumour activity, toxicity in silico and molecular modelling studies.

Rosales PF, Marinho FF, Gower A, Chiarello M, Canci B, Roesch-Ely M, Paula FR, Moura S. Rosales PF, et al. Among authors: paula fr. Bioorg Chem. 2019 Apr;85:66-74. doi: 10.1016/j.bioorg.2018.12.016. Epub 2018 Dec 15. Bioorg Chem. 2019. PMID: 30599414 Review.

6

Synthesis, activity, and molecular modeling studies of 1,2,3-triazole derivatives from natural phenylpropanoids as new trypanocidal agents.

de Souza TB, Caldas IS, Paula FR, Rodrigues CC, Carvalho DT, Dias DF. de Souza TB, et al. Among authors: paula fr. Chem Biol Drug Des. 2020 Jan;95(1):124-129. doi: 10.1111/cbdd.13628. Epub 2019 Oct 20. Chem Biol Drug Des. 2020. PMID: 31569301

7

Efficient synthesis and antitumor evaluation of 4-aminomethyl-N-arylpyrazoles: Discovery of potent and selective agents for ovarian cancer.

da Silva MJV, Jacomini AP, Figueiredo MC, Back DF, Foglio MA, Ruiz ALTG, Paula FR, Rosa FA. da Silva MJV, et al. Among authors: paula fr. Bioorg Med Chem. 2021 Jan 1;29:115835. doi: 10.1016/j.bmc.2020.115835. Epub 2020 Nov 4. Bioorg Med Chem. 2021. PMID: 33214037 Free article.

8

In vitro and in silico toxicity evaluation of bioactive 4'-aminochalcone derivatives.

Mariño PA, Pereira DB, Santi G, de Souza RO, Faoro D, de Oliveira LF, Machado MM, Paula FR. Mariño PA, et al. Among authors: paula fr. Drug Chem Toxicol. 2016;39(2):147-52. doi: 10.3109/01480545.2015.1056881. Epub 2015 Jul 7. Drug Chem Toxicol. 2016. PMID: 26154124

9

Insights on 3D Structures of Potential Drug-targeting Proteins of SARS-CoV-2: Application of Cavity Search and Molecular Docking.

Fernandes MS, da Silva FS, Freitas ACSG, de Melo EB, Trossini GHG, Paula FR. Fernandes MS, et al. Among authors: paula fr. Mol Inform. 2021 Feb;40(2):e2000096. doi: 10.1002/minf.202000096. Epub 2020 Oct 20. Mol Inform. 2021. PMID: 32750187 Free PMC article.

10

In vitro and in silico antioxidant and toxicological activities of Achyrocline satureioides.

Salgueiro AC, Folmer V, da Rosa HS, Costa MT, Boligon AA, Paula FR, Roos DH, Puntel GO. Salgueiro AC, et al. Among authors: paula fr. J Ethnopharmacol. 2016 Dec 24;194:6-14. doi: 10.1016/j.jep.2016.08.048. Epub 2016 Aug 27. J Ethnopharmacol. 2016. PMID: 27575777 Free article.

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