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Type 2 and interferon inflammation strongly regulate SARS-CoV-2 related gene expression in the airway epithelium.
Sajuthi SP, DeFord P, Jackson ND, Montgomery MT, Everman JL, Rios CL, Pruesse E, Nolin JD, Plender EG, Wechsler ME, Mak AC, Eng C, Salazar S, Medina V, Wohlford EM, Huntsman S, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, Rice KM, Kumar R, Oh S, Rodriguez-Santana J, Burchard EG, Seibold MA. Sajuthi SP, et al. bioRxiv [Preprint]. 2020 Apr 10:2020.04.09.034454. doi: 10.1101/2020.04.09.034454. bioRxiv. 2020. Update in: Nat Commun. 2020 Oct 12;11(1):5139. doi: 10.1038/s41467-020-18781-2 PMID: 32511326 Free PMC article. Updated. Preprint.
Type 2 and interferon inflammation regulate SARS-CoV-2 entry factor expression in the airway epithelium.
Sajuthi SP, DeFord P, Li Y, Jackson ND, Montgomery MT, Everman JL, Rios CL, Pruesse E, Nolin JD, Plender EG, Wechsler ME, Mak ACY, Eng C, Salazar S, Medina V, Wohlford EM, Huntsman S, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, Rice KM, Kumar R, Oh S, Rodriguez-Santana J, Burchard EG, Seibold MA. Sajuthi SP, et al. Nat Commun. 2020 Oct 12;11(1):5139. doi: 10.1038/s41467-020-18781-2. Nat Commun. 2020. PMID: 33046696 Free PMC article.
Genome-Wide Analysis Reveals Mucociliary Remodeling of the Nasal Airway Epithelium Induced by Urban PM2.5.
Montgomery MT, Sajuthi SP, Cho SH, Everman JL, Rios CL, Goldfarbmuren KC, Jackson ND, Saef B, Cromie M, Eng C, Medina V, Elhawary JR, Oh SS, Rodriguez-Santana J, Vladar EK, Burchard EG, Seibold MA. Montgomery MT, et al. Among authors: sajuthi sp. Am J Respir Cell Mol Biol. 2020 Aug;63(2):172-184. doi: 10.1165/rcmb.2019-0454OC. Am J Respir Cell Mol Biol. 2020. PMID: 32275839 Free PMC article.
Single-Cell and Population Transcriptomics Reveal Pan-epithelial Remodeling in Type 2-High Asthma.
Jackson ND, Everman JL, Chioccioli M, Feriani L, Goldfarbmuren KC, Sajuthi SP, Rios CL, Powell R, Armstrong M, Gomez J, Michel C, Eng C, Oh SS, Rodriguez-Santana J, Cicuta P, Reisdorph N, Burchard EG, Seibold MA. Jackson ND, et al. Among authors: sajuthi sp. Cell Rep. 2020 Jul 7;32(1):107872. doi: 10.1016/j.celrep.2020.107872. Cell Rep. 2020. PMID: 32640237 Free PMC article.
Lung Function in African American Children with Asthma Is Associated with Novel Regulatory Variants of the KIT Ligand KITLG/SCF and Gene-By-Air-Pollution Interaction.
Mak ACY, Sajuthi S, Joo J, Xiao S, Sleiman PM, White MJ, Lee EY, Saef B, Hu D, Gui H, Keys KL, Lurmann F, Jain D, Abecasis G, Kang HM, Nickerson DA, Germer S, Zody MC, Winterkorn L, Reeves C, Huntsman S, Eng C, Salazar S, Oh SS, Gilliland FD, Chen Z, Kumar R, Martínez FD, Wu AC, Ziv E, Hakonarson H, Himes BE, Williams LK, Seibold MA, Burchard EG. Mak ACY, et al. Genetics. 2020 Jul;215(3):869-886. doi: 10.1534/genetics.120.303231. Epub 2020 Apr 23. Genetics. 2020. PMID: 32327564 Free PMC article.
Whole-Genome Sequencing Identifies Novel Functional Loci Associated with Lung Function in Puerto Rican Youth.
Lee EY, Mak ACY, Hu D, Sajuthi S, White MJ, Keys KL, Eckalbar W, Bonser L, Huntsman S, Urbanek C, Eng C, Jain D, Abecasis G, Kang HM, Germer S, Zody MC, Nickerson DA, Erle D, Ziv E, Rodriguez-Santana J, Seibold MA, Burchard EG. Lee EY, et al. Am J Respir Crit Care Med. 2020 Oct 1;202(7):962-972. doi: 10.1164/rccm.202002-0351OC. Am J Respir Crit Care Med. 2020. PMID: 32459537 Free PMC article.
Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology.
Sajuthi SP, Everman JL, Jackson ND, Saef B, Rios CL, Moore CM, Mak ACY, Eng C, Fairbanks-Mahnke A, Salazar S, Elhawary J, Huntsman S, Medina V, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, Rice KM, Kumar R, Zaitlen NA, Oh S; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Rodríguez-Santana J, Burchard EG, Seibold MA. Sajuthi SP, et al. Nat Commun. 2022 Mar 28;13(1):1632. doi: 10.1038/s41467-022-28973-7. Nat Commun. 2022. PMID: 35347136 Free PMC article.
Author Correction: Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology.
Sajuthi SP, Everman JL, Jackson ND, Saef B, Rios CL, Moore CM, Mak ACY, Eng C, Fairbanks-Mahnke A, Salazar S, Elhawary J, Huntsman S, Medina V, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, Rice KM, Kumar R, Zaitlen NA, Oh S; NHLBI Trans–Omics for Precision Medicine (TOPMed) Consortium; Rodríguez-Santana J, Burchard EG, Seibold MA. Sajuthi SP, et al. Nat Commun. 2022 Oct 3;13(1):5806. doi: 10.1038/s41467-022-33097-z. Nat Commun. 2022. PMID: 36192399 Free PMC article. No abstract available.
32 results