Appel SH - Search Results

1

Immunosuppressive Functions of M2 Macrophages Derived from iPSCs of Patients with ALS and Healthy Controls.

Zhao W, Beers DR, Thonhoff JR, Thome AD, Faridar A, Wang J, Wen S, Ornelas L, Sareen D, Goodridge HS, Svendsen CN, Appel SH. Zhao W, et al. Among authors: appel sh. iScience. 2020 Jun 26;23(6):101192. doi: 10.1016/j.isci.2020.101192. Epub 2020 May 23. iScience. 2020. PMID: 32521508 Free PMC article.

2

Immunoglobulin Fc gamma receptor promotes immunoglobulin uptake, immunoglobulin-mediated calcium increase, and neurotransmitter release in motor neurons.

Mohamed HA, Mosier DR, Zou LL, Siklós L, Alexianu ME, Engelhardt JI, Beers DR, Le WD, Appel SH. Mohamed HA, et al. Among authors: appel sh. J Neurosci Res. 2002 Jul 1;69(1):110-6. doi: 10.1002/jnr.10271. J Neurosci Res. 2002. PMID: 12111822

3

PARP expression is increased in astrocytes but decreased in motor neurons in the spinal cord of sporadic ALS patients.

Kim SH, Henkel JS, Beers DR, Sengun IS, Simpson EP, Goodman JC, Engelhardt JI, Siklós L, Appel SH. Kim SH, et al. Among authors: appel sh. J Neuropathol Exp Neurol. 2003 Jan;62(1):88-103. doi: 10.1093/jnen/62.1.88. J Neuropathol Exp Neurol. 2003. PMID: 12528821

4

Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue.

Henkel JS, Engelhardt JI, Siklós L, Simpson EP, Kim SH, Pan T, Goodman JC, Siddique T, Beers DR, Appel SH. Henkel JS, et al. Among authors: appel sh. Ann Neurol. 2004 Feb;55(2):221-35. doi: 10.1002/ana.10805. Ann Neurol. 2004. PMID: 14755726

5

Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism.

Zhao W, Xie W, Le W, Beers DR, He Y, Henkel JS, Simpson EP, Yen AA, Xiao Q, Appel SH. Zhao W, et al. Among authors: appel sh. J Neuropathol Exp Neurol. 2004 Sep;63(9):964-77. doi: 10.1093/jnen/63.9.964. J Neuropathol Exp Neurol. 2004. PMID: 15453095

6

The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS.

Henkel JS, Beers DR, Siklós L, Appel SH. Henkel JS, et al. Among authors: appel sh. Mol Cell Neurosci. 2006 Mar;31(3):427-37. doi: 10.1016/j.mcn.2005.10.016. Epub 2005 Dec 5. Mol Cell Neurosci. 2006. PMID: 16337133

7

Protective effects of an anti-inflammatory cytokine, interleukin-4, on motoneuron toxicity induced by activated microglia.

Zhao W, Xie W, Xiao Q, Beers DR, Appel SH. Zhao W, et al. Among authors: appel sh. J Neurochem. 2006 Nov;99(4):1176-87. doi: 10.1111/j.1471-4159.2006.04172.x. Epub 2006 Oct 2. J Neurochem. 2006. PMID: 17018025 Free article.

8

Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis.

Beers DR, Henkel JS, Xiao Q, Zhao W, Wang J, Yen AA, Siklos L, McKercher SR, Appel SH. Beers DR, et al. Among authors: appel sh. Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):16021-6. doi: 10.1073/pnas.0607423103. Epub 2006 Oct 16. Proc Natl Acad Sci U S A. 2006. PMID: 17043238 Free PMC article.

9

Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia.

Xiao Q, Zhao W, Beers DR, Yen AA, Xie W, Henkel JS, Appel SH. Xiao Q, et al. Among authors: appel sh. J Neurochem. 2007 Sep;102(6):2008-2019. doi: 10.1111/j.1471-4159.2007.04677.x. Epub 2007 Jun 7. J Neurochem. 2007. PMID: 17555556 Free article.

10

Novel therapeutic targets in neurodegenerative diseases: lessons from amyotrophic lateral sclerosis.

Appel SH, Beers DR, Henkel JS, Zhao W. Appel SH, et al. Curr Neurol Neurosci Rep. 2008 Sep;8(5):353-5. doi: 10.1007/s11910-008-0054-6. Curr Neurol Neurosci Rep. 2008. PMID: 18713569 Review. No abstract available.

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