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Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia.
Vu T, Straube J, Porter AH, Bywater M, Song A, Ling V, Cooper L, Pali G, Bruedigam C, Jacquelin S, Green J, Magor G, Perkins A, Chalk AM, Walkley CR, Heidel FH, Mukhopadhyay P, Cloonan N, Gröschel S, Mallm JP, Fröhling S, Scholl C, Lane SW. Vu T, et al. Among authors: chalk am. Nat Commun. 2020 Jun 15;11(1):3021. doi: 10.1038/s41467-020-16840-2. Nat Commun. 2020. PMID: 32541670 Free PMC article.
The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis.
Smeets MF, DeLuca E, Wall M, Quach JM, Chalk AM, Deans AJ, Heierhorst J, Purton LE, Izon DJ, Walkley CR. Smeets MF, et al. Among authors: chalk am. J Clin Invest. 2014 Aug;124(8):3551-65. doi: 10.1172/JCI75334. Epub 2014 Jun 24. J Clin Invest. 2014. PMID: 24960165 Free PMC article.
RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself.
Liddicoat BJ, Piskol R, Chalk AM, Ramaswami G, Higuchi M, Hartner JC, Li JB, Seeburg PH, Walkley CR. Liddicoat BJ, et al. Among authors: chalk am. Science. 2015 Sep 4;349(6252):1115-20. doi: 10.1126/science.aac7049. Epub 2015 Jul 23. Science. 2015. PMID: 26275108 Free PMC article.
41 results