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Page 1
P2Y14 Receptor Antagonists Reverse Chronic Neuropathic Pain in a Mouse Model.
Mufti F, Jung YH, Giancotti LA, Yu J, Chen Z, Phung NB, Jacobson KA, Salvemini D. Mufti F, et al. Among authors: giancotti la. ACS Med Chem Lett. 2020 Apr 30;11(6):1281-1286. doi: 10.1021/acsmedchemlett.0c00115. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32551012 Free PMC article.
Dysregulation of sphingolipid metabolism contributes to bortezomib-induced neuropathic pain.
Stockstill K, Doyle TM, Yan X, Chen Z, Janes K, Little JW, Braden K, Lauro F, Giancotti LA, Harada CM, Yadav R, Xiao WH, Lionberger JM, Neumann WL, Bennett GJ, Weng HR, Spiegel S, Salvemini D. Stockstill K, et al. Among authors: giancotti la. J Exp Med. 2018 May 7;215(5):1301-1313. doi: 10.1084/jem.20170584. Epub 2018 Apr 27. J Exp Med. 2018. PMID: 29703731 Free PMC article.
Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain.
Chen Z, Doyle TM, Luongo L, Largent-Milnes TM, Giancotti LA, Kolar G, Squillace S, Boccella S, Walker JK, Pendleton A, Spiegel S, Neumann WL, Vanderah TW, Salvemini D. Chen Z, et al. Among authors: giancotti la. Proc Natl Acad Sci U S A. 2019 May 21;116(21):10557-10562. doi: 10.1073/pnas.1820466116. Epub 2019 May 8. Proc Natl Acad Sci U S A. 2019. PMID: 31068460 Free PMC article.
GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents.
Yosten GL, Harada CM, Haddock C, Giancotti LA, Kolar GR, Patel R, Guo C, Chen Z, Zhang J, Doyle TM, Dickenson AH, Samson WK, Salvemini D. Yosten GL, et al. Among authors: giancotti la. J Clin Invest. 2020 May 1;130(5):2587-2592. doi: 10.1172/JCI133270. J Clin Invest. 2020. PMID: 31999650 Free PMC article.
Antioxidant modulation of sirtuin 3 during acute inflammatory pain: The ROS control.
Ilari S, Giancotti LA, Lauro F, Dagostino C, Gliozzi M, Malafoglia V, Sansone L, Palma E, Tafani M, Russo MA, Tomino C, Fini M, Salvemini D, Mollace V, Muscoli C. Ilari S, et al. Among authors: giancotti la. Pharmacol Res. 2020 Jul;157:104851. doi: 10.1016/j.phrs.2020.104851. Epub 2020 May 11. Pharmacol Res. 2020. PMID: 32423865 Free article.
GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain.
Braden K, Giancotti LA, Chen Z, DeLeon C, Latzo N, Boehn T, D'Cunha N, Thompson BM, Doyle TM, McDonald JG, Walker JK, Kolar GR, Arnatt CK, Salvemini D. Braden K, et al. Among authors: giancotti la. J Pharmacol Exp Ther. 2020 Nov;375(2):367-375. doi: 10.1124/jpet.120.000105. Epub 2020 Sep 10. J Pharmacol Exp Ther. 2020. PMID: 32913007 Free PMC article.
Protective Effect of Antioxidants in Nitric Oxide/COX-2 Interaction during Inflammatory Pain: The Role of Nitration.
Ilari S, Dagostino C, Malafoglia V, Lauro F, Giancotti LA, Spila A, Proietti S, Ventrice D, Rizzo M, Gliozzi M, Palma E, Guadagni F, Salvemini D, Mollace V, Muscoli C. Ilari S, et al. Among authors: giancotti la. Antioxidants (Basel). 2020 Dec 16;9(12):1284. doi: 10.3390/antiox9121284. Antioxidants (Basel). 2020. PMID: 33339104 Free PMC article.
Adenosine A3 agonists reverse neuropathic pain via T cell-mediated production of IL-10.
Durante M, Squillace S, Lauro F, Giancotti LA, Coppi E, Cherchi F, Di Cesare Mannelli L, Ghelardini C, Kolar G, Wahlman C, Opejin A, Xiao C, Reitman ML, Tosh DK, Hawiger D, Jacobson KA, Salvemini D. Durante M, et al. Among authors: giancotti la. J Clin Invest. 2021 Apr 1;131(7):e139299. doi: 10.1172/JCI139299. J Clin Invest. 2021. PMID: 33621215 Free PMC article.
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