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A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models.
Loontiens S, Vanhauwaert S, Depestel L, Dewyn G, Van Loocke W, Moore FE, Garcia EG, Batchelor L, Borga C, Squiban B, Malone-Perez M, Volders PJ, Olexiouk V, Van Vlierberghe P, Langenau DM, Frazer JK, Durinck K, Speleman F. Loontiens S, et al. Among authors: depestel l. Leukemia. 2020 Dec;34(12):3398-3403. doi: 10.1038/s41375-020-0938-2. Epub 2020 Jun 26. Leukemia. 2020. PMID: 32591643 Free PMC article. No abstract available.
Purification of high-quality RNA from a small number of fluorescence activated cell sorted zebrafish cells for RNA sequencing purposes.
Loontiens S, Depestel L, Vanhauwaert S, Dewyn G, Gistelinck C, Verboom K, Van Loocke W, Matthijssens F, Willaert A, Vandesompele J, Speleman F, Durinck K. Loontiens S, et al. Among authors: depestel l. BMC Genomics. 2019 Mar 20;20(1):228. doi: 10.1186/s12864-019-5608-2. BMC Genomics. 2019. PMID: 30894119 Free PMC article.
PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation.
Loontiens S, Dolens AC, Strubbe S, Van de Walle I, Moore FE, Depestel L, Vanhauwaert S, Matthijssens F, Langenau DM, Speleman F, Van Vlierberghe P, Durinck K, Taghon T. Loontiens S, et al. Among authors: depestel l. Front Cell Dev Biol. 2020 Nov 4;8:599472. doi: 10.3389/fcell.2020.599472. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33251223 Free PMC article.
RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition.
Nunes C, Depestel L, Mus L, Keller KM, Delhaye L, Louwagie A, Rishfi M, Whale A, Kara N, Andrews SR, Dela Cruz F, You D, Siddiquee A, Cologna CT, De Craemer S, Dolman E, Bartenhagen C, De Vloed F, Sanders E, Eggermont A, Bekaert SL, Van Loocke W, Bek JW, Dewyn G, Loontiens S, Van Isterdael G, Decaesteker B, Tilleman L, Van Nieuwerburgh F, Vermeirssen V, Van Neste C, Ghesquiere B, Goossens S, Eyckerman S, De Preter K, Fischer M, Houseley J, Molenaar J, De Wilde B, Roberts SS, Durinck K, Speleman F. Nunes C, et al. Among authors: depestel l. Sci Adv. 2022 Jul 15;8(28):eabn1382. doi: 10.1126/sciadv.abn1382. Epub 2022 Jul 13. Sci Adv. 2022. PMID: 35857500 Free PMC article.