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Repositioning of leishmanicidal [1,2,3]Triazolo[1,5-a]pyridinium salts for Chagas disease treatment: Trypanosoma cruzi cell death involving mitochondrial membrane depolarisation and Fe-SOD inhibition.
Martín-Escolano R, Martín-Escolano J, Ballesteros-Garrido R, Cirauqui N, Abarca B, Rosales MJ, Sánchez-Moreno M, Ballesteros R, Marín C. Martín-Escolano R, et al. Parasitol Res. 2020 Sep;119(9):2943-2954. doi: 10.1007/s00436-020-06779-0. Epub 2020 Jul 1. Parasitol Res. 2020. PMID: 32607710
In vitro antileishmanial activity and iron superoxide dismutase inhibition of arylamine Mannich base derivatives.
Martin-Montes A, Santivañez-Veliz M, Moreno-Viguri E, Martín-Escolano R, Jiménez-Montes C, Lopez-Gonzalez C, Marín C, Sanmartín C, Gutiérrez Sánchez R, Sánchez-Moreno M, Pérez-Silanes S. Martin-Montes A, et al. Parasitology. 2017 Nov;144(13):1783-1790. doi: 10.1017/S0031182017001123. Epub 2017 Aug 9. Parasitology. 2017. PMID: 28789716 Free article.
Synthesis and Biological in vitro and in vivo Evaluation of 2-(5-Nitroindazol-1-yl)ethylamines and Related Compounds as Potential Therapeutic Alternatives for Chagas Disease.
Martín-Escolano R, Aguilera-Venegas B, Marín C, Martín-Montes Á, Martín-Escolano J, Medina-Carmona E, Arán VJ, Sánchez-Moreno M. Martín-Escolano R, et al. ChemMedChem. 2018 Oct 8;13(19):2104-2118. doi: 10.1002/cmdc.201800512. Epub 2018 Sep 4. ChemMedChem. 2018. PMID: 30098232 Free article.
In Vivo Biological Evaluation of a Synthetic Royleanone Derivative as a Promising Fast-Acting Trypanocidal Agent by Inducing Mitochondrial-Dependent Necrosis.
Martín-Escolano R, Guardia JJ, Martín-Escolano J, Cirauqui N, Fernández A, Rosales MJ, Chahboun R, Sánchez-Moreno M, Alvarez-Manzaneda E, Marín C. Martín-Escolano R, et al. J Nat Prod. 2020 Dec 24;83(12):3571-3583. doi: 10.1021/acs.jnatprod.0c00651. Epub 2020 Nov 30. J Nat Prod. 2020. PMID: 33253573
Selenium Derivatives as Promising Therapy for Chagas Disease: In Vitro and In Vivo Studies.
Martín-Escolano R, Etxebeste-Mitxeltorena M, Martín-Escolano J, Plano D, Rosales MJ, Espuelas S, Moreno E, Sánchez-Moreno M, Sanmartín C, Marín C. Martín-Escolano R, et al. ACS Infect Dis. 2021 Jun 11;7(6):1727-1738. doi: 10.1021/acsinfecdis.1c00048. Epub 2021 Apr 19. ACS Infect Dis. 2021. PMID: 33871252 Free PMC article.
39 results