Kolaja KL - Search Results

1

Human ileal organoid model recapitulates clinical incidence of diarrhea associated with small molecule drugs.

Belair DG, Visconti RJ, Hong M, Marella M, Peters MF, Scott CW, Kolaja KL. Belair DG, et al. Among authors: kolaja kl. Toxicol In Vitro. 2020 Oct;68:104928. doi: 10.1016/j.tiv.2020.104928. Epub 2020 Jul 3. Toxicol In Vitro. 2020. PMID: 32622998 Free article.

2

Developing in vitro assays to transform gastrointestinal safety assessment: potential for microphysiological systems.

Peters MF, Choy AL, Pin C, Leishman DJ, Moisan A, Ewart L, Guzzie-Peck PJ, Sura R, Keller DA, Scott CW, Kolaja KL. Peters MF, et al. Among authors: kolaja kl. Lab Chip. 2020 Apr 7;20(7):1177-1190. doi: 10.1039/c9lc01107b. Epub 2020 Mar 4. Lab Chip. 2020. PMID: 32129356 Review.

3

Investigation Into the Role of ERK in Tyrosine Kinase Inhibitor-Induced Neuropathy.

Belair DG, Sudak K, Connelly K, Collins ND, Kopytek SJ, Kolaja KL. Belair DG, et al. Among authors: kolaja kl. Toxicol Sci. 2021 May 27;181(2):160-174. doi: 10.1093/toxsci/kfab033. Toxicol Sci. 2021. PMID: 33749749 Clinical Trial.

4

Human stem cell-derived cardiomyocytes in cellular impedance assays: bringing cardiotoxicity screening to the front line.

Peters MF, Lamore SD, Guo L, Scott CW, Kolaja KL. Peters MF, et al. Among authors: kolaja kl. Cardiovasc Toxicol. 2015 Apr;15(2):127-39. doi: 10.1007/s12012-014-9268-9. Cardiovasc Toxicol. 2015. PMID: 25134468 Review.

5

Cardiovascular Toxicity Induced by Kinase Inhibitors: Mechanisms and Preclinical Approaches.

Lamore SD, Kohnken RA, Peters MF, Kolaja KL. Lamore SD, et al. Among authors: kolaja kl. Chem Res Toxicol. 2020 Jan 21;33(1):125-136. doi: 10.1021/acs.chemrestox.9b00387. Epub 2020 Jan 10. Chem Res Toxicol. 2020. PMID: 31840498 Review.

6

Thalidomide Inhibits Human iPSC Mesendoderm Differentiation by Modulating CRBN-dependent Degradation of SALL4.

Belair DG, Lu G, Waller LE, Gustin JA, Collins ND, Kolaja KL. Belair DG, et al. Among authors: kolaja kl. Sci Rep. 2020 Feb 18;10(1):2864. doi: 10.1038/s41598-020-59542-x. Sci Rep. 2020. PMID: 32071327 Free PMC article.

7

A functional three-dimensional microphysiological human model of myeloma bone disease.

Visconti RJ, Kolaja K, Cottrell JA. Visconti RJ, et al. J Bone Miner Res. 2021 Oct;36(10):1914-1930. doi: 10.1002/jbmr.4404. Epub 2021 Jul 27. J Bone Miner Res. 2021. PMID: 34173283 Free article.

8

Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes.

Guo L, Abrams RM, Babiarz JE, Cohen JD, Kameoka S, Sanders MJ, Chiao E, Kolaja KL. Guo L, et al. Among authors: kolaja kl. Toxicol Sci. 2011 Sep;123(1):281-9. doi: 10.1093/toxsci/kfr158. Epub 2011 Jun 20. Toxicol Sci. 2011. PMID: 21693436

9

In vitro to in vivo concordance of a high throughput assay of bone marrow toxicity across a diverse set of drug candidates.

Olaharski AJ, Uppal H, Cooper M, Platz S, Zabka TS, Kolaja KL. Olaharski AJ, et al. Among authors: kolaja kl. Toxicol Lett. 2009 Jul 24;188(2):98-103. doi: 10.1016/j.toxlet.2009.03.012. Epub 2009 Mar 25. Toxicol Lett. 2009. PMID: 19446241

10

Drug discovery: computer model predicts side effects.

Kolaja K. Kolaja K. Nature. 2012 Jun 10;486(7403):326-7. doi: 10.1038/nature11198. Nature. 2012. PMID: 22722185 No abstract available.

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