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Synthesis and preliminary evaluation of 4-hydroxy-6-(3-[11C]methoxyphenethyl)pyridazin-3(2H)-one, a 11C-labeled d-amino acid oxidase (DAAO) inhibitor for PET imaging.
Deng X, Zhang Y, Chen Z, Kumata K, Van R, Rong J, Shao T, Hatori A, Mori W, Yu Q, Hu K, Fujinaga M, Wey HY, Shao Y, Josephson L, Murtas G, Pollegioni L, Zhang MR, Liang S. Deng X, et al. Among authors: pollegioni l. Bioorg Med Chem Lett. 2020 Aug 15;30(16):127326. doi: 10.1016/j.bmcl.2020.127326. Epub 2020 Jun 9. Bioorg Med Chem Lett. 2020. PMID: 32631531 Free PMC article.
Structure-function relationships in human D-amino acid oxidase.
Sacchi S, Caldinelli L, Cappelletti P, Pollegioni L, Molla G. Sacchi S, et al. Among authors: pollegioni l. Amino Acids. 2012 Nov;43(5):1833-50. doi: 10.1007/s00726-012-1345-4. Epub 2012 Aug 3. Amino Acids. 2012. PMID: 22865246 Review.
Structural, kinetic, and pharmacodynamic mechanisms of D-amino acid oxidase inhibition by small molecules.
Hopkins SC, Heffernan ML, Saraswat LD, Bowen CA, Melnick L, Hardy LW, Orsini MA, Allen MS, Koch P, Spear KL, Foglesong RJ, Soukri M, Chytil M, Fang QK, Jones SW, Varney MA, Panatier A, Oliet SH, Pollegioni L, Piubelli L, Molla G, Nardini M, Large TH. Hopkins SC, et al. Among authors: pollegioni l. J Med Chem. 2013 May 9;56(9):3710-24. doi: 10.1021/jm4002583. Epub 2013 Apr 30. J Med Chem. 2013. PMID: 23631755
Human d-amino acid oxidase: The inactive G183R variant.
Murtas G, Caldinelli L, Cappelletti P, Sacchi S, Pollegioni L. Murtas G, et al. Among authors: pollegioni l. Biochim Biophys Acta Proteins Proteom. 2018 Jul;1866(7):822-830. doi: 10.1016/j.bbapap.2017.12.007. Epub 2017 Dec 21. Biochim Biophys Acta Proteins Proteom. 2018. PMID: 29274788
Biochemical Properties of Human D-Amino Acid Oxidase.
Murtas G, Sacchi S, Valentino M, Pollegioni L. Murtas G, et al. Among authors: pollegioni l. Front Mol Biosci. 2017 Dec 15;4:88. doi: 10.3389/fmolb.2017.00088. eCollection 2017. Front Mol Biosci. 2017. PMID: 29326945 Free PMC article.
243 results