Zhang MR - Search Results

1

Synthesis and preliminary evaluation of 4-hydroxy-6-(3-[¹¹C]methoxyphenethyl)pyridazin-3(2H)-one, a ¹¹C-labeled d-amino acid oxidase (DAAO) inhibitor for PET imaging.

Deng X, Zhang Y, Chen Z, Kumata K, Van R, Rong J, Shao T, Hatori A, Mori W, Yu Q, Hu K, Fujinaga M, Wey HY, Shao Y, Josephson L, Murtas G, Pollegioni L, Zhang MR, Liang S. Deng X, et al. Among authors: zhang mr, zhang y. Bioorg Med Chem Lett. 2020 Aug 15;30(16):127326. doi: 10.1016/j.bmcl.2020.127326. Epub 2020 Jun 9. Bioorg Med Chem Lett. 2020. PMID: 32631531 Free PMC article.

2

Synthesis, in vitro and in vivo pharmacology of a C-11 labeled analog of CP-101,606, (+/-)threo-1-(4-hydroxyphenyl)-2-[4-hydroxy-4-(p-[11C]methoxyphenyl)piperidino]-1-propanol, as a PET tracer for NR2B subunit-containing NMDA receptors.

Haradahira T, Maeda J, Okauchi T, Zhang MR, Hojo J, Kida T, Arai T, Yamamoto F, Sasaki S, Maeda M, Suzuki K, Suhara T. Haradahira T, et al. Among authors: zhang mr. Nucl Med Biol. 2002 Jul;29(5):517-25. doi: 10.1016/s0969-8051(02)00301-3. Nucl Med Biol. 2002. PMID: 12088721

3

[18F]FMDAA1106 and [18F]FEDAA1106: two positron-emitter labeled ligands for peripheral benzodiazepine receptor (PBR).

Zhang MR, Maeda J, Furutsuka K, Yoshida Y, Ogawa M, Suhara T, Suzuki K. Zhang MR, et al. Bioorg Med Chem Lett. 2003 Jan 20;13(2):201-4. doi: 10.1016/s0960-894x(02)00886-7. Bioorg Med Chem Lett. 2003. PMID: 12482423

4

N-[18F]fluoroethyl-4-piperidyl acetate ([18F]FEtP4A): A PET tracer for imaging brain acetylcholinesterase in vivo.

Zhang MR, Furutsuka K, Maeda J, Kikuchi T, Kida T, Okauchi T, Irie T, Suzuki K. Zhang MR, et al. Bioorg Med Chem. 2003 Jun 12;11(12):2519-27. doi: 10.1016/s0968-0896(03)00177-9. Bioorg Med Chem. 2003. PMID: 12757720

5

N-[18F]fluoroethylpiperidin-4-ylmethyl butyrate: a novel radiotracer for quantifying brain butyrylcholinesterase activity by positron emission tomography.

Kikuchi T, Zhang MR, Ikota N, Fukushi K, Okamura T, Suzuki K, Arano Y, Irie T. Kikuchi T, et al. Among authors: zhang mr. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1927-30. doi: 10.1016/j.bmcl.2004.01.080. Bioorg Med Chem Lett. 2004. PMID: 15050629

6

Development of a new radioligand, N-(5-fluoro-2-phenoxyphenyl)-N-(2-[18F]fluoroethyl-5-methoxybenzyl)acetamide, for pet imaging of peripheral benzodiazepine receptor in primate brain.

Zhang MR, Maeda J, Ogawa M, Noguchi J, Ito T, Yoshida Y, Okauchi T, Obayashi S, Suhara T, Suzuki K. Zhang MR, et al. J Med Chem. 2004 Apr 22;47(9):2228-35. doi: 10.1021/jm0304919. J Med Chem. 2004. PMID: 15084121

7

Novel peripheral benzodiazepine receptor ligand [11C]DAA1106 for PET: an imaging tool for glial cells in the brain.

Maeda J, Suhara T, Zhang MR, Okauchi T, Yasuno F, Ikoma Y, Inaji M, Nagai Y, Takano A, Obayashi S, Suzuki K. Maeda J, et al. Among authors: zhang mr. Synapse. 2004 Jun 15;52(4):283-91. doi: 10.1002/syn.20027. Synapse. 2004. PMID: 15103694

8

Synthesis and evaluation of N-(5-fluoro-2-phenoxyphenyl)-N-(2-[(18)F]fluoromethoxy-d(2)-5-methoxybenzyl)acetamide: a deuterium-substituted radioligand for peripheral benzodiazepine receptor.

Zhang MR, Maeda J, Ito T, Okauchi T, Ogawa M, Noguchi J, Suhara T, Halldin C, Suzuki K. Zhang MR, et al. Bioorg Med Chem. 2005 Mar 1;13(5):1811-8. doi: 10.1016/j.bmc.2004.11.058. Bioorg Med Chem. 2005. PMID: 15698799

9

N-[18F] fluoroethylpiperidin-4ylmethyl acetate, a novel lipophilic acetylcholine analogue for PET measurement of brain acetylcholinesterase activity.

Kikuchi T, Zhang MR, Ikota N, Fukushi K, Okamura T, Suzuki K, Arano Y, Irie T. Kikuchi T, et al. Among authors: zhang mr. J Med Chem. 2005 Apr 7;48(7):2577-83. doi: 10.1021/jm049100w. J Med Chem. 2005. PMID: 15801847

10

[2-11C]isopropyl-, [1-11C]ethyl-, and [11C]methyl-labeled phenoxyphenyl acetamide derivatives as positron emission tomography ligands for the peripheral benzodiazepine receptor: radiosynthesis, uptake, and in vivo binding in brain.

Zhang MR, Ogawa M, Maeda J, Ito T, Noguchi J, Kumata K, Okauchi T, Suhara T, Suzuki K. Zhang MR, et al. J Med Chem. 2006 May 4;49(9):2735-42. doi: 10.1021/jm060006k. J Med Chem. 2006. PMID: 16640334

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