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Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability.
Dawes JM, Weir GA, Middleton SJ, Patel R, Chisholm KI, Pettingill P, Peck LJ, Sheridan J, Shakir A, Jacobson L, Gutierrez-Mecinas M, Galino J, Walcher J, Kühnemund J, Kuehn H, Sanna MD, Lang B, Clark AJ, Themistocleous AC, Iwagaki N, West SJ, Werynska K, Carroll L, Trendafilova T, Menassa DA, Giannoccaro MP, Coutinho E, Cervellini I, Tewari D, Buckley C, Leite MI, Wildner H, Zeilhofer HU, Peles E, Todd AJ, McMahon SB, Dickenson AH, Lewin GR, Vincent A, Bennett DL. Dawes JM, et al. Among authors: clark aj. Neuron. 2018 Feb 21;97(4):806-822.e10. doi: 10.1016/j.neuron.2018.01.033. Epub 2018 Feb 8. Neuron. 2018. PMID: 29429934 Free PMC article.
The Role of Voltage-Gated Sodium Channels in Pain Signaling.
Bennett DL, Clark AJ, Huang J, Waxman SG, Dib-Hajj SD. Bennett DL, et al. Among authors: clark aj. Physiol Rev. 2019 Apr 1;99(2):1079-1151. doi: 10.1152/physrev.00052.2017. Physiol Rev. 2019. PMID: 30672368 Free article. Review.
Defining the Functional Role of NaV1.7 in Human Nociception.
McDermott LA, Weir GA, Themistocleous AC, Segerdahl AR, Blesneac I, Baskozos G, Clark AJ, Millar V, Peck LJ, Ebner D, Tracey I, Serra J, Bennett DL. McDermott LA, et al. Among authors: clark aj. Neuron. 2019 Mar 6;101(5):905-919.e8. doi: 10.1016/j.neuron.2019.01.047. Epub 2019 Feb 19. Neuron. 2019. PMID: 30795902 Free PMC article.
An iPSC model of hereditary sensory neuropathy-1 reveals L-serine-responsive deficits in neuronal ganglioside composition and axoglial interactions.
Clark AJ, Kugathasan U, Baskozos G, Priestman DA, Fugger N, Lone MA, Othman A, Chu KH, Blesneac I, Wilson ER, Laurà M, Kalmar B, Greensmith L, Hornemann T, Platt FM, Reilly MM, Bennett DL. Clark AJ, et al. Cell Rep Med. 2021 Jul 21;2(7):100345. doi: 10.1016/j.xcrm.2021.100345. eCollection 2021 Jul 20. Cell Rep Med. 2021. PMID: 34337561 Free PMC article.
A humanized chemogenetic system inhibits murine pain-related behavior and hyperactivity in human sensory neurons.
Perez-Sanchez J, Middleton SJ, Pattison LA, Hilton H, Ali Awadelkareem M, Zuberi SR, Renke MB, Hu H, Yang X, Clark AJ, St John Smith E, Bennett DL. Perez-Sanchez J, et al. Among authors: clark aj. Sci Transl Med. 2023 Oct 4;15(716):eadh3839. doi: 10.1126/scitranslmed.adh3839. Epub 2023 Oct 4. Sci Transl Med. 2023. PMID: 37792955 Free PMC article.
918 results