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The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA.
Thapa D, Wu K, Stoner MW, Xie B, Zhang M, Manning JR, Lu Z, Li JH, Chen Y, Gucek M, Playford MP, Mehta NN, Harmon D, O'Doherty RM, Jurczak MJ, Sack MN, Scott I. Thapa D, et al. Among authors: scott i. J Biol Chem. 2018 Nov 16;293(46):17676-17684. doi: 10.1074/jbc.AC118.005462. Epub 2018 Oct 15. J Biol Chem. 2018. PMID: 30323061 Free PMC article.
Adropin treatment restores cardiac glucose oxidation in pre-diabetic obese mice.
Thapa D, Xie B, Zhang M, Stoner MW, Manning JR, Huckestein BR, Edmunds LR, Mullett SJ, McTiernan CF, Wendell SG, Jurczak MJ, Scott I. Thapa D, et al. Among authors: scott i. J Mol Cell Cardiol. 2019 Apr;129:174-178. doi: 10.1016/j.yjmcc.2019.02.012. Epub 2019 Feb 26. J Mol Cell Cardiol. 2019. PMID: 30822408 Free PMC article.
Empagliflozin restores cardiac metabolic flexibility in diet-induced obese C57BL6/J mice.
Xie B, Ramirez W, Mills AM, Huckestein BR, Anderson M, Pangburn MM, Lang EY, Mullet SJ, Chuan BW, Guo L, Sipula I, O'Donnell CP, Wendell SG, Scott I, Jurczak MJ. Xie B, et al. Among authors: scott i. Curr Res Physiol. 2022 May 28;5:232-239. doi: 10.1016/j.crphys.2022.05.003. eCollection 2022. Curr Res Physiol. 2022. PMID: 35677213 Free PMC article.
Myocardial brain-derived neurotrophic factor regulates cardiac bioenergetics through the transcription factor Yin Yang 1.
Yang X, Zhang M, Xie B, Peng Z, Manning JR, Zimmerman R, Wang Q, Wei AC, Khalifa M, Reynolds M, Jin J, Om M, Zhu G, Bedja D, Jiang H, Jurczak M, Shiva S, Scott I, O'Rourke B, Kass DA, Paolocci N, Feng N. Yang X, et al. Among authors: scott i. Cardiovasc Res. 2023 Mar 31;119(2):571-586. doi: 10.1093/cvr/cvac096. Cardiovasc Res. 2023. PMID: 35704040 Free PMC article.
1,480 results