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526 results

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CRISPR-CasΦ from huge phages is a hypercompact genome editor.
Pausch P, Al-Shayeb B, Bisom-Rapp E, Tsuchida CA, Li Z, Cress BF, Knott GJ, Jacobsen SE, Banfield JF, Doudna JA. Pausch P, et al. Among authors: jacobsen se. Science. 2020 Jul 17;369(6501):333-337. doi: 10.1126/science.abb1400. Science. 2020. PMID: 32675376 Free PMC article.
Epigenetic reprogramming in plant and animal development.
Feng S, Jacobsen SE, Reik W. Feng S, et al. Among authors: jacobsen se. Science. 2010 Oct 29;330(6004):622-7. doi: 10.1126/science.1190614. Science. 2010. PMID: 21030646 Free PMC article. Review.
MBD5 and MBD6 couple DNA methylation to gene silencing through the J-domain protein SILENZIO.
Ichino L, Boone BA, Strauskulage L, Harris CJ, Kaur G, Gladstone MA, Tan M, Feng S, Jami-Alahmadi Y, Duttke SH, Wohlschlegel JA, Cheng X, Redding S, Jacobsen SE. Ichino L, et al. Among authors: jacobsen se. Science. 2021 Jun 3:eabg6130. doi: 10.1126/science.abg6130. Online ahead of print. Science. 2021. PMID: 34083448 Free PMC article.
CRISPR-Cas-mediated transcriptional control and epi-mutagenesis.
Gardiner J, Ghoshal B, Wang M, Jacobsen SE. Gardiner J, et al. Among authors: jacobsen se. Plant Physiol. 2022 Mar 28;188(4):1811-1824. doi: 10.1093/plphys/kiac033. Plant Physiol. 2022. PMID: 35134247 Free PMC article. Review.
Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors.
Al-Shayeb B, Skopintsev P, Soczek KM, Stahl EC, Li Z, Groover E, Smock D, Eggers AR, Pausch P, Cress BF, Huang CJ, Staskawicz B, Savage DF, Jacobsen SE, Banfield JF, Doudna JA. Al-Shayeb B, et al. Among authors: jacobsen se. Cell. 2022 Nov 23;185(24):4574-4586.e16. doi: 10.1016/j.cell.2022.10.020. Cell. 2022. PMID: 36423580 Free article.
Genome editing in plants using the compact editor CasΦ.
Li Z, Zhong Z, Wu Z, Pausch P, Al-Shayeb B, Amerasekera J, Doudna JA, Jacobsen SE. Li Z, et al. Among authors: jacobsen se. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2216822120. doi: 10.1073/pnas.2216822120. Epub 2023 Jan 18. Proc Natl Acad Sci U S A. 2023. PMID: 36652483 Free PMC article.
The MOM1 complex recruits the RdDM machinery via MORC6 to establish de novo DNA methylation.
Li Z, Wang M, Zhong Z, Gallego-Bartolomé J, Feng S, Jami-Alahmadi Y, Wang X, Wohlschlegel J, Bischof S, Long JA, Jacobsen SE. Li Z, et al. Among authors: jacobsen se. bioRxiv [Preprint]. 2023 Jan 10:2023.01.10.523455. doi: 10.1101/2023.01.10.523455. bioRxiv. 2023. Update in: Nat Commun. 2023 Jul 12;14(1):4135. doi: 10.1038/s41467-023-39751-4. PMID: 36711532 Free PMC article. Updated. Preprint.
526 results