Unsinger J - Search Results

1

Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections.

Remy KE, Mazer M, Striker DA, Ellebedy AH, Walton AH, Unsinger J, Blood TM, Mudd PA, Yi DJ, Mannion DA, Osborne DF, Martin RS, Anand NJ, Bosanquet JP, Blood J, Drewry AM, Caldwell CC, Turnbull IR, Brakenridge SC, Moldwawer LL, Hotchkiss RS. Remy KE, et al. Among authors: unsinger j. JCI Insight. 2020 Sep 3;5(17):e140329. doi: 10.1172/jci.insight.140329. JCI Insight. 2020. PMID: 32687484 Free PMC article.

2

The role of TCR engagement and activation-induced cell death in sepsis-induced T cell apoptosis.

Unsinger J, Herndon JM, Davis CG, Muenzer JT, Hotchkiss RS, Ferguson TA. Unsinger J, et al. J Immunol. 2006 Dec 1;177(11):7968-73. doi: 10.4049/jimmunol.177.11.7968. J Immunol. 2006. PMID: 17114469

3

Pneumonia after cecal ligation and puncture: a clinically relevant "two-hit" model of sepsis.

Muenzer JT, Davis CG, Dunne BS, Unsinger J, Dunne WM, Hotchkiss RS. Muenzer JT, et al. Among authors: unsinger j. Shock. 2006 Dec;26(6):565-70. doi: 10.1097/01.shk.0000235130.82363.ed. Shock. 2006. PMID: 17117130

4

Multiple triggers of cell death in sepsis: death receptor and mitochondrial-mediated apoptosis.

Chang KC, Unsinger J, Davis CG, Schwulst SJ, Muenzer JT, Strasser A, Hotchkiss RS. Chang KC, et al. Among authors: unsinger j. FASEB J. 2007 Mar;21(3):708-19. doi: 10.1096/fj.06-6805com. Epub 2007 Feb 16. FASEB J. 2007. PMID: 17307841

5

Bim siRNA decreases lymphocyte apoptosis and improves survival in sepsis.

Schwulst SJ, Muenzer JT, Peck-Palmer OM, Chang KC, Davis CG, McDonough JS, Osborne DF, Walton AH, Unsinger J, McDunn JE, Hotchkiss RS. Schwulst SJ, et al. Among authors: unsinger j. Shock. 2008 Aug;30(2):127-34. doi: 10.1097/shk.0b013e318162cf17. Shock. 2008. PMID: 18197142

6

Deletion of MyD88 markedly attenuates sepsis-induced T and B lymphocyte apoptosis but worsens survival.

Peck-Palmer OM, Unsinger J, Chang KC, Davis CG, McDunn JE, Hotchkiss RS. Peck-Palmer OM, et al. Among authors: unsinger j. J Leukoc Biol. 2008 Apr;83(4):1009-18. doi: 10.1189/jlb.0807528. Epub 2008 Jan 22. J Leukoc Biol. 2008. PMID: 18211965

7

Modulation of the Bcl-2 family blocks sepsis-induced depletion of dendritic cells and macrophages.

Peck-Palmer OM, Unsinger J, Chang KC, McDonough JS, Perlman H, McDunn JE, Hotchkiss RS. Peck-Palmer OM, et al. Among authors: unsinger j. Shock. 2009 Apr;31(4):359-66. doi: 10.1097/SHK.0b013e31818ba2a2. Shock. 2009. PMID: 18838943 Free PMC article.

8

Targeted delivery of siRNA to cell death proteins in sepsis.

Brahmamdam P, Watanabe E, Unsinger J, Chang KC, Schierding W, Hoekzema AS, Zhou TT, McDonough JS, Holemon H, Heidel JD, Coopersmith CM, McDunn JE, Hotchkiss RS. Brahmamdam P, et al. Among authors: unsinger j. Shock. 2009 Aug;32(2):131-9. doi: 10.1097/SHK.0b013e318194bcee. Shock. 2009. PMID: 19033888 Free PMC article.

9

Differential lymphopenia-induced homeostatic proliferation for CD4+ and CD8+ T cells following septic injury.

Unsinger J, Kazama H, McDonough JS, Hotchkiss RS, Ferguson TA. Unsinger J, et al. J Leukoc Biol. 2009 Mar;85(3):382-90. doi: 10.1189/jlb.0808491. Epub 2008 Dec 30. J Leukoc Biol. 2009. PMID: 19088177 Free PMC article.

10

Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice.

Unsinger J, McDonough JS, Shultz LD, Ferguson TA, Hotchkiss RS. Unsinger J, et al. J Leukoc Biol. 2009 Aug;86(2):219-27. doi: 10.1189/jlb.1008615. Epub 2009 Apr 15. J Leukoc Biol. 2009. PMID: 19369639 Free PMC article.

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