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Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity.
Vrettos EI, Valverde IE, Mascarin A, Pallier PN, Cerofolini L, Fragai M, Parigi G, Hirmiz B, Bekas N, Grob NM, Stylos EΚ, Shaye H, Del Borgo M, Aguilar MI, Magnani F, Syed N, Crook T, Waqif E, Ghazaly E, Cherezov V, Widdop RE, Luchinat C, Michael-Titus AT, Mindt TL, Tzakos AG. Vrettos EI, et al. Among authors: cherezov v. Chemistry. 2020 Aug 21;26(47):10690-10694. doi: 10.1002/chem.202000924. Epub 2020 Jul 21. Chemistry. 2020. PMID: 32691857
Structural basis of the activation of a metabotropic GABA receptor.
Shaye H, Ishchenko A, Lam JH, Han GW, Xue L, Rondard P, Pin JP, Katritch V, Gati C, Cherezov V. Shaye H, et al. Among authors: cherezov v. Nature. 2020 Aug;584(7820):298-303. doi: 10.1038/s41586-020-2408-4. Epub 2020 Jun 17. Nature. 2020. PMID: 32555460 Free PMC article.
Molecular mechanisms of metabotropic GABAB receptor function.
Shaye H, Stauch B, Gati C, Cherezov V. Shaye H, et al. Among authors: cherezov v. Sci Adv. 2021 May 28;7(22):eabg3362. doi: 10.1126/sciadv.abg3362. Print 2021 May. Sci Adv. 2021. PMID: 34049877 Free PMC article. Review.
Structural basis of GABA reuptake inhibition.
Motiwala Z, Aduri NG, Shaye H, Han GW, Lam JH, Katritch V, Cherezov V, Gati C. Motiwala Z, et al. Among authors: cherezov v. Nature. 2022 Jun;606(7915):820-826. doi: 10.1038/s41586-022-04814-x. Epub 2022 Jun 8. Nature. 2022. PMID: 35676483 Free PMC article.
Publisher Correction: Structural basis of GABA reuptake inhibition.
Motiwala Z, Aduri NG, Shaye H, Han GW, Lam JH, Katritch V, Cherezov V, Gati C. Motiwala Z, et al. Among authors: cherezov v. Nature. 2022 Aug;608(7921):E15. doi: 10.1038/s41586-022-05080-7. Nature. 2022. PMID: 35840686 No abstract available.
Inhibition of the angiotensin II type 2 receptor AT2R is a novel therapeutic strategy for glioblastoma.
Perryman R, Renziehausen A, Shaye H, Kostagianni AD, Tsiailanis AD, Thorne T, Chatziathanasiadou MV, Sivolapenko GB, El Mubarak MA, Han GW, Zarzycka B, Katritch V, Lebon G, Lo Nigro C, Lattanzio L, Morse SV, Choi JJ, O'Neill K, Kanaki Z, Klinakis A, Crook T, Cherezov V, Tzakos AG, Syed N. Perryman R, et al. Among authors: cherezov v. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2116289119. doi: 10.1073/pnas.2116289119. Epub 2022 Aug 2. Proc Natl Acad Sci U S A. 2022. PMID: 35917342 Free PMC article.
Structural basis for selectivity and diversity in angiotensin II receptors.
Zhang H, Han GW, Batyuk A, Ishchenko A, White KL, Patel N, Sadybekov A, Zamlynny B, Rudd MT, Hollenstein K, Tolstikova A, White TA, Hunter MS, Weierstall U, Liu W, Babaoglu K, Moore EL, Katz RD, Shipman JM, Garcia-Calvo M, Sharma S, Sheth P, Soisson SM, Stevens RC, Katritch V, Cherezov V. Zhang H, et al. Among authors: cherezov v. Nature. 2017 Apr 20;544(7650):327-332. doi: 10.1038/nature22035. Epub 2017 Apr 5. Nature. 2017. PMID: 28379944 Free PMC article.
Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors.
Gusach A, Luginina A, Marin E, Brouillette RL, Besserer-Offroy É, Longpré JM, Ishchenko A, Popov P, Patel N, Fujimoto T, Maruyama T, Stauch B, Ergasheva M, Romanovskaia D, Stepko A, Kovalev K, Shevtsov M, Gordeliy V, Han GW, Katritch V, Borshchevskiy V, Sarret P, Mishin A, Cherezov V. Gusach A, et al. Among authors: cherezov v. Nat Commun. 2019 Dec 6;10(1):5573. doi: 10.1038/s41467-019-13348-2. Nat Commun. 2019. PMID: 31811124 Free PMC article.
171 results