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A Physiologically-Based Pharmacokinetic Model for the Prediction of "Half-Life Extension" and "Catch and Release" Monoclonal Antibody Pharmacokinetics.
Jones HM, Tolsma J, Zhang Z, Jasper P, Luo H, Weber GL, Wright K, Bard J, Bell R, Messing D, Kelleher K, Piche-Nicholas N, Webster R. Jones HM, et al. Among authors: wright k. CPT Pharmacometrics Syst Pharmacol. 2020 Sep;9(9):534-541. doi: 10.1002/psp4.12547. Epub 2020 Aug 17. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 32697437 Free PMC article.
Translational Pharmacokinetic/Pharmacodynamic Characterization and Target-Mediated Drug Disposition Modeling of an Anti-Tissue Factor Pathway Inhibitor Antibody, PF-06741086.
Parng C, Singh P, Pittman DD, Wright K, Leary B, Patel-Hett S, Rakhe S, Stejskal J, Peraza M, Dufield D, Murphy JE, Webster R. Parng C, et al. Among authors: wright k. J Pharm Sci. 2018 Jul;107(7):1995-2004. doi: 10.1016/j.xphs.2018.03.010. Epub 2018 Mar 20. J Pharm Sci. 2018. PMID: 29571739
Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition.
Telliez JB, Dowty ME, Wang L, Jussif J, Lin T, Li L, Moy E, Balbo P, Li W, Zhao Y, Crouse K, Dickinson C, Symanowicz P, Hegen M, Banker ME, Vincent F, Unwalla R, Liang S, Gilbert AM, Brown MF, Hayward M, Montgomery J, Yang X, Bauman J, Trujillo JI, Casimiro-Garcia A, Vajdos FF, Leung L, Geoghegan KF, Quazi A, Xuan D, Jones L, Hett E, Wright K, Clark JD, Thorarensen A. Telliez JB, et al. Among authors: wright k. ACS Chem Biol. 2016 Dec 16;11(12):3442-3451. doi: 10.1021/acschembio.6b00677. Epub 2016 Nov 10. ACS Chem Biol. 2016. PMID: 27791347
M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy with Comorbid Traits.
Ochoa S, Rasquel-Oliveira FS, McKinnon B, Haro M, Subramaniam S, Yu P, Coetzee S, Anglesio MS, Wright KN, Meyer R, Gargett CE, Mortlock S, Montgomery GW, Rogers MS, Lawrenson K. Ochoa S, et al. Among authors: wright kn. bioRxiv [Preprint]. 2024 Nov 22:2024.11.21.624726. doi: 10.1101/2024.11.21.624726. bioRxiv. 2024. PMID: 39605445 Free PMC article. Preprint.
2,973 results