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Page 1
Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition.
Pasciuto E, Burton OT, Roca CP, Lagou V, Rajan WD, Theys T, Mancuso R, Tito RY, Kouser L, Callaerts-Vegh Z, de la Fuente AG, Prezzemolo T, Mascali LG, Brajic A, Whyte CE, Yshii L, Martinez-Muriana A, Naughton M, Young A, Moudra A, Lemaitre P, Poovathingal S, Raes J, De Strooper B, Fitzgerald DC, Dooley J, Liston A. Pasciuto E, et al. Among authors: poovathingal s. Cell. 2020 Aug 6;182(3):625-640.e24. doi: 10.1016/j.cell.2020.06.026. Epub 2020 Jul 22. Cell. 2020. PMID: 32702313 Free PMC article.
Stem-cell-derived human microglia transplanted in mouse brain to study human disease.
Mancuso R, Van Den Daele J, Fattorelli N, Wolfs L, Balusu S, Burton O, Liston A, Sierksma A, Fourne Y, Poovathingal S, Arranz-Mendiguren A, Sala Frigerio C, Claes C, Serneels L, Theys T, Perry VH, Verfaillie C, Fiers M, De Strooper B. Mancuso R, et al. Among authors: poovathingal s. Nat Neurosci. 2019 Dec;22(12):2111-2116. doi: 10.1038/s41593-019-0525-x. Epub 2019 Oct 28. Nat Neurosci. 2019. PMID: 31659342
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation.
Yshii L, Pasciuto E, Bielefeld P, Mascali L, Lemaitre P, Marino M, Dooley J, Kouser L, Verschoren S, Lagou V, Kemps H, Gervois P, de Boer A, Burton OT, Wahis J, Verhaert J, Tareen SHK, Roca CP, Singh K, Whyte CE, Kerstens A, Callaerts-Vegh Z, Poovathingal S, Prezzemolo T, Wierda K, Dashwood A, Xie J, Van Wonterghem E, Creemers E, Aloulou M, Gsell W, Abiega O, Munck S, Vandenbroucke RE, Bronckaers A, Lemmens R, De Strooper B, Van Den Bosch L, Himmelreich U, Fitzsimons CP, Holt MG, Liston A. Yshii L, et al. Among authors: poovathingal s. Nat Immunol. 2022 Jun;23(6):878-891. doi: 10.1038/s41590-022-01208-z. Epub 2022 May 26. Nat Immunol. 2022. PMID: 35618831 Free PMC article.
A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain.
Davie K, Janssens J, Koldere D, De Waegeneer M, Pech U, Kreft Ł, Aibar S, Makhzami S, Christiaens V, Bravo González-Blas C, Poovathingal S, Hulselmans G, Spanier KI, Moerman T, Vanspauwen B, Geurs S, Voet T, Lammertyn J, Thienpont B, Liu S, Konstantinides N, Fiers M, Verstreken P, Aerts S. Davie K, et al. Among authors: poovathingal s. Cell. 2018 Aug 9;174(4):982-998.e20. doi: 10.1016/j.cell.2018.05.057. Epub 2018 Jun 18. Cell. 2018. PMID: 29909982 Free PMC article.
Xenotransplanted Human Cortical Neurons Reveal Species-Specific Development and Functional Integration into Mouse Visual Circuits.
Linaro D, Vermaercke B, Iwata R, Ramaswamy A, Libé-Philippot B, Boubakar L, Davis BA, Wierda K, Davie K, Poovathingal S, Penttila PA, Bilheu A, De Bruyne L, Gall D, Conzelmann KK, Bonin V, Vanderhaeghen P. Linaro D, et al. Among authors: poovathingal s. Neuron. 2019 Dec 4;104(5):972-986.e6. doi: 10.1016/j.neuron.2019.10.002. Epub 2019 Nov 21. Neuron. 2019. PMID: 31761708 Free PMC article.
Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures.
Sousa C, Golebiewska A, Poovathingal SK, Kaoma T, Pires-Afonso Y, Martina S, Coowar D, Azuaje F, Skupin A, Balling R, Biber K, Niclou SP, Michelucci A. Sousa C, et al. Among authors: poovathingal sk. EMBO Rep. 2018 Nov;19(11):e46171. doi: 10.15252/embr.201846171. Epub 2018 Sep 11. EMBO Rep. 2018. PMID: 30206190 Free PMC article.
Identification of genomic enhancers through spatial integration of single-cell transcriptomics and epigenomics.
Bravo González-Blas C, Quan XJ, Duran-Romaña R, Taskiran II, Koldere D, Davie K, Christiaens V, Makhzami S, Hulselmans G, de Waegeneer M, Mauduit D, Poovathingal S, Aibar S, Aerts S. Bravo González-Blas C, et al. Among authors: poovathingal s. Mol Syst Biol. 2020 May;16(5):e9438. doi: 10.15252/msb.20209438. Mol Syst Biol. 2020. PMID: 32431014 Free PMC article.
Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma.
Wouters J, Kalender-Atak Z, Minnoye L, Spanier KI, De Waegeneer M, Bravo González-Blas C, Mauduit D, Davie K, Hulselmans G, Najem A, Dewaele M, Pedri D, Rambow F, Makhzami S, Christiaens V, Ceyssens F, Ghanem G, Marine JC, Poovathingal S, Aerts S. Wouters J, et al. Among authors: poovathingal s. Nat Cell Biol. 2020 Aug;22(8):986-998. doi: 10.1038/s41556-020-0547-3. Epub 2020 Aug 3. Nat Cell Biol. 2020. PMID: 32753671
Comparative analysis of antibody- and lipid-based multiplexing methods for single-cell RNA-seq.
Mylka V, Matetovici I, Poovathingal S, Aerts J, Vandamme N, Seurinck R, Verstaen K, Hulselmans G, Van den Hoecke S, Scheyltjens I, Movahedi K, Wils H, Reumers J, Van Houdt J, Aerts S, Saeys Y. Mylka V, et al. Among authors: poovathingal s. Genome Biol. 2022 Feb 16;23(1):55. doi: 10.1186/s13059-022-02628-8. Genome Biol. 2022. PMID: 35172874 Free PMC article.
50 results