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Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6.
Pérez-Areales FJ, Garrido M, Aso E, Bartolini M, De Simone A, Espargaró A, Ginex T, Sabate R, Pérez B, Andrisano V, Puigoriol-Illamola D, Pallàs M, Luque FJ, Loza MI, Brea J, Ferrer I, Ciruela F, Messeguer A, Muñoz-Torrero D. Pérez-Areales FJ, et al. Among authors: pallas m. J Med Chem. 2020 Sep 10;63(17):9360-9390. doi: 10.1021/acs.jmedchem.0c00528. Epub 2020 Aug 11. J Med Chem. 2020. PMID: 32706255
Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
Camps P, Formosa X, Galdeano C, Gómez T, Muñoz-Torrero D, Scarpellini M, Viayna E, Badia A, Clos MV, Camins A, Pallàs M, Bartolini M, Mancini F, Andrisano V, Estelrich J, Lizondo M, Bidon-Chanal A, Luque FJ. Camps P, et al. Among authors: pallas m. J Med Chem. 2008 Jun 26;51(12):3588-98. doi: 10.1021/jm8001313. Epub 2008 Jun 3. J Med Chem. 2008. PMID: 18517184
Novel huprine derivatives with inhibitory activity toward β-amyloid aggregation and formation as disease-modifying anti-Alzheimer drug candidates.
Viayna E, Gómez T, Galdeano C, Ramírez L, Ratia M, Badia A, Clos MV, Verdaguer E, Junyent F, Camins A, Pallàs M, Bartolini M, Mancini F, Andrisano V, Arce MP, Rodríguez-Franco MI, Bidon-Chanal A, Luque FJ, Camps P, Muñoz-Torrero D. Viayna E, et al. Among authors: pallas m. ChemMedChem. 2010 Nov 8;5(11):1855-70. doi: 10.1002/cmdc.201000322. ChemMedChem. 2010. PMID: 20859987
High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents.
Petrov D, Pedrós I, Artiach G, Sureda FX, Barroso E, Pallàs M, Casadesús G, Beas-Zarate C, Carro E, Ferrer I, Vazquez-Carrera M, Folch J, Camins A. Petrov D, et al. Among authors: pallas m. Biochim Biophys Acta. 2015 Sep;1852(9):1687-99. doi: 10.1016/j.bbadis.2015.05.004. Epub 2015 May 21. Biochim Biophys Acta. 2015. PMID: 26003667 Free article.
Environmental Enrichment Modified Epigenetic Mechanisms in SAMP8 Mouse Hippocampus by Reducing Oxidative Stress and Inflammaging and Achieving Neuroprotection.
Griñan-Ferré C, Puigoriol-Illamola D, Palomera-Ávalos V, Pérez-Cáceres D, Companys-Alemany J, Camins A, Ortuño-Sahagún D, Rodrigo MT, Pallàs M. Griñan-Ferré C, et al. Among authors: pallas m. Front Aging Neurosci. 2016 Oct 18;8:241. doi: 10.3389/fnagi.2016.00241. eCollection 2016. Front Aging Neurosci. 2016. PMID: 27803663 Free PMC article.
317 results