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Page 1
4-(N-Alkyl- and -Acyl-amino)-1,2,4-triazole-3-thione Analogs as Metallo-β-Lactamase Inhibitors: Impact of 4-Linker on Potency and Spectrum of Inhibition.
Gavara L, Verdirosa F, Legru A, Mercuri PS, Nauton L, Sevaille L, Feller G, Berthomieu D, Sannio F, Marcoccia F, Tanfoni S, De Luca F, Gresh N, Galleni M, Docquier JD, Hernandez JF. Gavara L, et al. Among authors: sannio f. Biomolecules. 2020 Jul 23;10(8):1094. doi: 10.3390/biom10081094. Biomolecules. 2020. PMID: 32717907 Free PMC article.
Alkyl-guanidine Compounds as Potent Broad-Spectrum Antibacterial Agents: Chemical Library Extension and Biological Characterization.
Pasero C, D'Agostino I, De Luca F, Zamperini C, Deodato D, Truglio GI, Sannio F, Del Prete R, Ferraro T, Visaggio D, Mancini A, Guglielmi MB, Visca P, Docquier JD, Botta M. Pasero C, et al. Among authors: sannio f. J Med Chem. 2018 Oct 25;61(20):9162-9176. doi: 10.1021/acs.jmedchem.8b00619. Epub 2018 Oct 11. J Med Chem. 2018. PMID: 30265809
Virtual screening identifies broad-spectrum β-lactamase inhibitors with activity on clinically relevant serine- and metallo-carbapenemases.
Spyrakis F, Santucci M, Maso L, Cross S, Gianquinto E, Sannio F, Verdirosa F, De Luca F, Docquier JD, Cendron L, Tondi D, Venturelli A, Cruciani G, Costi MP. Spyrakis F, et al. Among authors: sannio f. Sci Rep. 2020 Jul 29;10(1):12763. doi: 10.1038/s41598-020-69431-y. Sci Rep. 2020. PMID: 32728062 Free PMC article.
4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors.
Gavara L, Sevaille L, De Luca F, Mercuri P, Bebrone C, Feller G, Legru A, Cerboni G, Tanfoni S, Baud D, Cutolo G, Bestgen B, Chelini G, Verdirosa F, Sannio F, Pozzi C, Benvenuti M, Kwapien K, Fischer M, Becker K, Frère JM, Mangani S, Gresh N, Berthomieu D, Galleni M, Docquier JD, Hernandez JF. Gavara L, et al. Among authors: sannio f. Eur J Med Chem. 2020 Dec 15;208:112720. doi: 10.1016/j.ejmech.2020.112720. Epub 2020 Aug 20. Eur J Med Chem. 2020. PMID: 32937203 Free article.
4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-β-lactamase inhibitors.
Gavara L, Legru A, Verdirosa F, Sevaille L, Nauton L, Corsica G, Mercuri PS, Sannio F, Feller G, Coulon R, De Luca F, Cerboni G, Tanfoni S, Chelini G, Galleni M, Docquier JD, Hernandez JF. Gavara L, et al. Among authors: sannio f. Bioorg Chem. 2021 Aug;113:105024. doi: 10.1016/j.bioorg.2021.105024. Epub 2021 May 26. Bioorg Chem. 2021. PMID: 34116340
1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity.
Legru A, Verdirosa F, Hernandez JF, Tassone G, Sannio F, Benvenuti M, Conde PA, Bossis G, Thomas CA, Crowder MW, Dillenberger M, Becker K, Pozzi C, Mangani S, Docquier JD, Gavara L. Legru A, et al. Among authors: sannio f. Eur J Med Chem. 2021 Dec 15;226:113873. doi: 10.1016/j.ejmech.2021.113873. Epub 2021 Oct 4. Eur J Med Chem. 2021. PMID: 34626878
Anatomy of an extensively drug-resistant Klebsiella pneumoniae outbreak in Tuscany, Italy.
Martin MJ, Corey BW, Sannio F, Hall LR, MacDonald U, Jones BT, Mills EG, Harless C, Stam J, Maybank R, Kwak Y, Schaufler K, Becker K, Hübner NO, Cresti S, Tordini G, Valassina M, Cusi MG, Bennett JW, Russo TA, McGann PT, Lebreton F, Docquier JD. Martin MJ, et al. Among authors: sannio f. Proc Natl Acad Sci U S A. 2021 Nov 30;118(48):e2110227118. doi: 10.1073/pnas.2110227118. Proc Natl Acad Sci U S A. 2021. PMID: 34819373 Free PMC article.
1,2,4-Triazole-3-Thione Analogues with a 2-Ethylbenzoic Acid at Position 4 as VIM-type Metallo-β-Lactamase Inhibitors.
Verdirosa F, Gavara L, Sevaille L, Tassone G, Corsica G, Legru A, Feller G, Chelini G, Mercuri PS, Tanfoni S, Sannio F, Benvenuti M, Cerboni G, De Luca F, Bouajila E, Vo Hoang Y, Licznar-Fajardo P, Galleni M, Pozzi C, Mangani S, Docquier JD, Hernandez JF. Verdirosa F, et al. Among authors: sannio f. ChemMedChem. 2022 Apr 5;17(7):e202100699. doi: 10.1002/cmdc.202100699. Epub 2022 Feb 4. ChemMedChem. 2022. PMID: 35050549
26 results