Xu C - Search Results

1

Pharmacokinetics and Pharmacodynamics of Subcutaneous Sarilumab and Intravenous Tocilizumab Following Single-Dose Administration in Patients With Active Rheumatoid Arthritis on Stable Methotrexate.

Paccaly AJ, Kovalenko P, Parrino J, Boyapati A, Xu C, van Hoogstraten H, Ishii T, Davis JD, DiCioccio AT. Paccaly AJ, et al. Among authors: xu c. J Clin Pharmacol. 2021 Jan;61(1):90-104. doi: 10.1002/jcph.1703. Epub 2020 Jul 29. J Clin Pharmacol. 2021. PMID: 32726514 Free PMC article. Clinical Trial.

2

A randomized, placebo-controlled study of the pharmacokinetics, pharmacodynamics, and tolerability of the oral JAK2 inhibitor fedratinib (SAR302503) in healthy volunteers.

Zhang M, Xu CR, Shamiyeh E, Liu F, Yin JY, von Moltke LL, Smith WB. Zhang M, et al. J Clin Pharmacol. 2014 Apr;54(4):415-21. doi: 10.1002/jcph.218. Epub 2013 Nov 16. J Clin Pharmacol. 2014. PMID: 24165976 Clinical Trial.

3

Effect of food on the bioavailability and tolerability of the JAK2-selective inhibitor fedratinib (SAR302503): Results from two phase I studies in healthy volunteers.

Zhang M, Xu C, Ma L, Shamiyeh E, Yin J, von Moltke LL, Smith WB. Zhang M, et al. Among authors: xu c. Clin Pharmacol Drug Dev. 2015 Jul;4(4):315-21. doi: 10.1002/cpdd.161. Epub 2014 Oct 27. Clin Pharmacol Drug Dev. 2015. PMID: 27136912 Clinical Trial.

4

Disease-Drug Interaction of Sarilumab and Simvastatin in Patients with Rheumatoid Arthritis.

Lee EB, Daskalakis N, Xu C, Paccaly A, Miller B, Fleischmann R, Bodrug I, Kivitz A. Lee EB, et al. Among authors: xu c. Clin Pharmacokinet. 2017 Jun;56(6):607-615. doi: 10.1007/s40262-016-0462-8. Clin Pharmacokinet. 2017. PMID: 27722854 Free PMC article. Clinical Trial.

5

Usability and Patient Preference Phase 3 Study of the Sarilumab Pen in Patients with Active Moderate-to-Severe Rheumatoid Arthritis.

Kivitz A, Baret-Cormel L, van Hoogstraten H, Wang S, Parrino J, Xu C, Stanislav M. Kivitz A, et al. Among authors: xu c. Rheumatol Ther. 2018 Jun;5(1):231-242. doi: 10.1007/s40744-017-0090-2. Epub 2017 Dec 5. Rheumatol Ther. 2018. PMID: 29209946 Free PMC article.

6

Pharmacokinetics of Tildrakizumab (MK-3222), an Anti-IL-23 Monoclonal Antibody, After Intravenous or Subcutaneous Administration in Healthy Subjects.

Khalilieh S, Hodsman P, Xu C, Tzontcheva A, Glasgow S, Montgomery D. Khalilieh S, et al. Among authors: xu c. Basic Clin Pharmacol Toxicol. 2018 Sep;123(3):294-300. doi: 10.1111/bcpt.13001. Epub 2018 Apr 20. Basic Clin Pharmacol Toxicol. 2018. PMID: 29510001 Free article. Clinical Trial.

7

Population Pharmacokinetics of Sarilumab in Patients with Rheumatoid Arthritis.

Xu C, Su Y, Paccaly A, Kanamaluru V. Xu C, et al. Clin Pharmacokinet. 2019 Nov;58(11):1455-1467. doi: 10.1007/s40262-019-00765-1. Clin Pharmacokinet. 2019. PMID: 31055792 Free PMC article. Clinical Trial.

8

Immunogenicity of Sarilumab Monotherapy in Patients with Rheumatoid Arthritis Who Were Inadequate Responders or Intolerant to Disease-Modifying Antirheumatic Drugs.

Wells AF, Parrino J, Mangan EK, Paccaly A, Lin Y, Xu C, Fan C, Graham NMH, van Hoogstraten H, Torri A. Wells AF, et al. Among authors: xu c. Rheumatol Ther. 2019 Sep;6(3):339-352. doi: 10.1007/s40744-019-0157-3. Epub 2019 May 14. Rheumatol Ther. 2019. PMID: 31090044 Free PMC article.

9

Population Pharmacokinetic-Pharmacodynamic Relationships of Sarilumab Using Disease Activity Score 28-Joint C-Reactive Protein and Absolute Neutrophil Counts in Patients with Rheumatoid Arthritis.

Ma L, Xu C, Paccaly A, Kanamaluru V. Ma L, et al. Among authors: xu c. Clin Pharmacokinet. 2020 Nov;59(11):1451-1466. doi: 10.1007/s40262-020-00899-7. Clin Pharmacokinet. 2020. PMID: 32451909 Free PMC article. Clinical Trial.

10

Population Pharmacodynamic Model of Neutrophil Margination and Tolerance to Describe Effect of Sarilumab on Absolute Neutrophil Count in Patients with Rheumatoid Arthritis.

Kovalenko P, Paccaly A, Boyapati A, Xu C, St John G, Nivens MC, Davis JD, Rippley R, DiCioccio AT. Kovalenko P, et al. Among authors: xu c. CPT Pharmacometrics Syst Pharmacol. 2020 Jul;9(7):405-416. doi: 10.1002/psp4.12534. Epub 2020 Jun 20. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 32453485 Free PMC article.

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