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Single-dose evaluation of safety, tolerability and pharmacokinetics of newly formulated hydromorphone immediate-release and hydrophilic matrix extended-release tablets in healthy Japanese subjects without co-administration of an opioid antagonist.
Toyama K, Uchida N, Ishizuka H, Sambe T, Kobayashi S. Toyama K, et al. Among authors: ishizuka h. J Clin Pharmacol. 2015 Sep;55(9):975-84. doi: 10.1002/jcph.501. Epub 2015 May 6. J Clin Pharmacol. 2015. PMID: 25807927 Clinical Trial.
A Randomized, Placebo-Controlled, Double-Blind Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Repeated Doses of Mirogabalin in Healthy Asian Volunteers.
Jansen M, Warrington S, Dishy V, Ohwada S, Johnson L, Brown K, Ishizuka H. Jansen M, et al. Among authors: ishizuka h. Clin Pharmacol Drug Dev. 2018 Aug;7(6):661-669. doi: 10.1002/cpdd.448. Epub 2018 Apr 17. Clin Pharmacol Drug Dev. 2018. PMID: 29663714 Clinical Trial.
Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Mirogabalin When Coadministered With Lorazepam, Zolpidem, Tramadol, or Ethanol: Results From Drug-Drug Interaction Studies in Healthy Subjects.
Jansen M, Mendell J, Currie A, Dow J, He L, Merante D, Dishy V, Ishizuka H, Zahir H. Jansen M, et al. Among authors: ishizuka h. Clin Pharmacol Drug Dev. 2018 Aug;7(6):597-612. doi: 10.1002/cpdd.582. Epub 2018 Jun 5. Clin Pharmacol Drug Dev. 2018. PMID: 29870596 Clinical Trial.
Absolute Bioavailability of Esaxerenone and Food Effects on its Pharmacokinetics After a Single Oral Dose in Healthy Japanese Subjects: An Open-Label Crossover Study.
Kurata A, Furuie H, Ishizuka T, Nakatsu T, Shimizu T, Kato M, Nishikawa Y, Ishizuka H. Kurata A, et al. Among authors: ishizuka h, ishizuka t. Adv Ther. 2019 Jul;36(7):1618-1627. doi: 10.1007/s12325-019-00956-z. Epub 2019 May 22. Adv Ther. 2019. PMID: 31119692 Free PMC article. Clinical Trial.
202 results