Kale VP - Search Results

1

Evaluation of chronic toxicity of cyclocreatine, a creatine analog, in Sprague Dawley rat after oral gavage administration for up to 26 weeks.

Kale VP, Wallery J, Novak J, Gibbs S, Bourdi M, Do MT, McKew JC, Terse PS. Kale VP, et al. Regul Toxicol Pharmacol. 2020 Nov;117:104750. doi: 10.1016/j.yrtph.2020.104750. Epub 2020 Aug 1. Regul Toxicol Pharmacol. 2020. PMID: 32745584

2

Preclinical toxicity evaluation of JD5037, a peripherally restricted CB₁ receptor inverse agonist, in rats and dogs for treatment of nonalcoholic steatohepatitis.

Kale VP, Gibbs S, Taylor JA, Zmarowski A, Novak J, Patton K, Sparrow B, Gorospe J, Anand S, Cinar R, Kunos G, Chorvat RJ, Terse PS. Kale VP, et al. Regul Toxicol Pharmacol. 2019 Dec;109:104483. doi: 10.1016/j.yrtph.2019.104483. Epub 2019 Sep 30. Regul Toxicol Pharmacol. 2019. PMID: 31580887 Free PMC article.

3

Evaluation of chronic toxicity of cyclocreatine in beagle dogs after oral gavage administration for up to 23 weeks.

Wallery JJ, Kale VP, Novak J, Gibbs S, Do MT, McKew JC, Terse PS. Wallery JJ, et al. Among authors: kale vp. Toxicol Appl Pharmacol. 2021 Nov 1;430:115680. doi: 10.1016/j.taap.2021.115680. Epub 2021 Aug 17. Toxicol Appl Pharmacol. 2021. PMID: 34411581 Free PMC article.

4

Practical Considerations in Determining Adversity and the No-Observed-Adverse-Effect-Level (NOAEL) in Nonclinical Safety Studies: Challenges, Perspectives and Case Studies.

Kale VP, Bebenek I, Ghantous H, Kapeghian J, Singh BP, Thomas LJ. Kale VP, et al. Int J Toxicol. 2022 Mar-Apr;41(2):143-162. doi: 10.1177/10915818211073047. Epub 2022 Mar 1. Int J Toxicol. 2022. PMID: 35230174

5

Gene-directed enzyme prodrug therapy.

Zhang J, Kale V, Chen M. Zhang J, et al. AAPS J. 2015 Jan;17(1):102-10. doi: 10.1208/s12248-014-9675-7. Epub 2014 Oct 23. AAPS J. 2015. PMID: 25338741 Free PMC article. Review.

6

Old drugs, new uses: Drug repurposing in hematological malignancies.

Kale VP, Habib H, Chitren R, Patel M, Pramanik KC, Jonnalagadda SC, Challagundla K, Pandey MK. Kale VP, et al. Semin Cancer Biol. 2021 Jan;68:242-248. doi: 10.1016/j.semcancer.2020.03.005. Epub 2020 Mar 6. Semin Cancer Biol. 2021. PMID: 32151704 Review.

7

Targeting ion channels for cancer therapy by repurposing the approved drugs.

Kale VP, Amin SG, Pandey MK. Kale VP, et al. Biochim Biophys Acta. 2015 Oct;1848(10 Pt B):2747-55. doi: 10.1016/j.bbamem.2015.03.034. Epub 2015 Apr 3. Biochim Biophys Acta. 2015. PMID: 25843679 Free article. Review.

8

Gambogic acid inhibits multiple myeloma mediated osteoclastogenesis through suppression of chemokine receptor CXCR4 signaling pathways.

Pandey MK, Kale VP, Song C, Sung SS, Sharma AK, Talamo G, Dovat S, Amin SG. Pandey MK, et al. Among authors: kale vp. Exp Hematol. 2014 Oct;42(10):883-96. doi: 10.1016/j.exphem.2014.07.261. Epub 2014 Jul 14. Exp Hematol. 2014. PMID: 25034231 Free article.

9

The regulatory roles of ROCK and MRCK kinases in the plasticity of cancer cell migration.

Kale VP, Hengst JA, Desai DH, Amin SG, Yun JK. Kale VP, et al. Cancer Lett. 2015 Jun 1;361(2):185-96. doi: 10.1016/j.canlet.2015.03.017. Epub 2015 Mar 18. Cancer Lett. 2015. PMID: 25796438 Review.

10

A novel selective multikinase inhibitor of ROCK and MRCK effectively blocks cancer cell migration and invasion.

Kale VP, Hengst JA, Desai DH, Dick TE, Choe KN, Colledge AL, Takahashi Y, Sung SS, Amin SG, Yun JK. Kale VP, et al. Cancer Lett. 2014 Nov 28;354(2):299-310. doi: 10.1016/j.canlet.2014.08.032. Epub 2014 Aug 27. Cancer Lett. 2014. PMID: 25172415 Free PMC article.

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