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Page 1
A Structure-Based Mechanism for DNA Entry into the Cohesin Ring.
Higashi TL, Eickhoff P, Sousa JS, Locke J, Nans A, Flynn HR, Snijders AP, Papageorgiou G, O'Reilly N, Chen ZA, O'Reilly FJ, Rappsilber J, Costa A, Uhlmann F. Higashi TL, et al. Among authors: papageorgiou g. Mol Cell. 2020 Sep 17;79(6):917-933.e9. doi: 10.1016/j.molcel.2020.07.013. Epub 2020 Aug 4. Mol Cell. 2020. PMID: 32755595 Free PMC article.
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease.
Milligan JC, Zeisner TU, Papageorgiou G, Joshi D, Soudy C, Ulferts R, Wu M, Lim CT, Tan KW, Weissmann F, Canal B, Fujisawa R, Deegan T, Nagaraj H, Bineva-Todd G, Basier C, Curran JF, Howell M, Beale R, Labib K, O'Reilly N, Diffley JFX. Milligan JC, et al. Among authors: papageorgiou g. Biochem J. 2021 Jul 16;478(13):2499-2515. doi: 10.1042/BCJ20210197. Biochem J. 2021. PMID: 34198327 Free PMC article.
MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG.
Fets L, Driscoll PC, Grimm F, Jain A, Nunes PM, Gounis M, Doglioni G, Papageorgiou G, Ragan TJ, Campos S, Silva Dos Santos M, MacRae JI, O'Reilly N, Wright AJ, Benes CH, Courtney KD, House D, Anastasiou D. Fets L, et al. Among authors: papageorgiou g. Nat Chem Biol. 2018 Nov;14(11):1032-1042. doi: 10.1038/s41589-018-0136-y. Epub 2018 Oct 8. Nat Chem Biol. 2018. PMID: 30297875 Free PMC article.
Automated synthesis of backbone protected peptides.
Abdel-Aal AB, Papageorgiou G, Quibell M, Offer J. Abdel-Aal AB, et al. Among authors: papageorgiou g. Chem Commun (Camb). 2014 Aug 7;50(61):8316-9. doi: 10.1039/c4cc03065f. Chem Commun (Camb). 2014. PMID: 24938489 Free PMC article.
Synthesis of Amide Backbone-Modified Peptides.
Abdel-Aal AM, Raz R, Papageorgiou G, Offer J. Abdel-Aal AM, et al. Among authors: papageorgiou g. Methods Mol Biol. 2020;2103:225-237. doi: 10.1007/978-1-0716-0227-0_15. Methods Mol Biol. 2020. PMID: 31879929
Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors.
Atkinson BN, Steadman D, Mahy W, Zhao Y, Sipthorp J, Bayle ED, Svensson F, Papageorgiou G, Jeganathan F, Frew S, Monaghan A, Bictash M, Jones EY, Fish PV. Atkinson BN, et al. Among authors: papageorgiou g. Bioorg Med Chem Lett. 2020 Feb 1;30(3):126751. doi: 10.1016/j.bmcl.2019.126751. Epub 2019 Oct 28. Bioorg Med Chem Lett. 2020. PMID: 31862412 Free PMC article.
311 results