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Identification and Optimization of Pyrrolidine Derivatives as Highly Potent Ghrelin Receptor Full Agonists.
J Med Chem. 2020 Sep 10;63(17):9705-9730. doi: 10.1021/acs.jmedchem.0c00828. Epub 2020 Aug 27.
J Med Chem. 2020.
PMID: 32787075
Characterisation of pharmacokinetics, safety and tolerability in a first-in-human study for AZD8154, a novel inhaled selective PI3Kγδ dual inhibitor targeting airway inflammatory disease.
Sadiq MW, Asimus S, Belvisi MG, Brailsford W, Fransson R, Fuhr R, Hagberg A, Hashemi M, Jellesmark Jensen T, Jonsson J, Keen C, Körnicke T, Kristensson C, Mäenpää J, Necander S, Nemes S, Betts J.
Sadiq MW, et al. Among authors: jellesmark jensen t.
Br J Clin Pharmacol. 2022 Jan;88(1):260-270. doi: 10.1111/bcp.14956. Epub 2021 Aug 8.
Br J Clin Pharmacol. 2022.
PMID: 34182611
Free article.
Clinical Trial.
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