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Disease-associated KIF3A variants alter gene methylation and expression impacting skin barrier and atopic dermatitis risk.
Stevens ML, Zhang Z, Johansson E, Ray S, Jagpal A, Ruff BP, Kothari A, He H, Martin LJ, Ji H, Wikenheiser-Brokamp K, Weirauch MT, Supp DM, Biagini Myers JM, Khurana Hershey GK. Stevens ML, et al. Among authors: weirauch mt. Nat Commun. 2020 Aug 14;11(1):4092. doi: 10.1038/s41467-020-17895-x. Nat Commun. 2020. PMID: 32796837 Free PMC article.
Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease.
Kottyan LC, Davis BP, Sherrill JD, Liu K, Rochman M, Kaufman K, Weirauch MT, Vaughn S, Lazaro S, Rupert AM, Kohram M, Stucke EM, Kemme KA, Magnusen A, He H, Dexheimer P, Chehade M, Wood RA, Pesek RD, Vickery BP, Fleischer DM, Lindbad R, Sampson HA, Mukkada VA, Putnam PE, Abonia JP, Martin LJ, Harley JB, Rothenberg ME. Kottyan LC, et al. Among authors: weirauch mt. Nat Genet. 2014 Aug;46(8):895-900. doi: 10.1038/ng.3033. Epub 2014 Jul 13. Nat Genet. 2014. PMID: 25017104 Free PMC article.
KIF3A genetic variation is associated with pediatric asthma in the presence of eczema independent of allergic rhinitis.
Johansson E, Biagini Myers JM, Martin LJ, He H, Pilipenko V, Mersha T, Weirauch M, Salomonis N, Ryan P, LeMasters GK, Bernstein DI, Lockey J, Khurana Hershey GK. Johansson E, et al. J Allergy Clin Immunol. 2017 Aug;140(2):595-598.e5. doi: 10.1016/j.jaci.2017.02.003. Epub 2017 Feb 24. J Allergy Clin Immunol. 2017. PMID: 28238750 Free PMC article. No abstract available.
Nasal DNA methylation is associated with childhood asthma.
Zhang X, Biagini Myers JM, Burleson JD, Ulm A, Bryan KS, Chen X, Weirauch MT, Baker TA, Butsch Kovacic MS, Ji H. Zhang X, et al. Among authors: weirauch mt. Epigenomics. 2018 May;10(5):629-641. doi: 10.2217/epi-2017-0127. Epub 2018 Apr 25. Epigenomics. 2018. PMID: 29692198 Free PMC article.
190 results