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A multiorganism pipeline for antiseizure drug discovery: Identification of chlorothymol as a novel γ-aminobutyric acidergic anticonvulsant.
Epilepsia. 2020 Oct;61(10):2106-2118. doi: 10.1111/epi.16644. Epub 2020 Aug 14.
Epilepsia. 2020.
PMID: 32797628
Free PMC article.
Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures.
Baxendale S, Holdsworth CJ, Meza Santoscoy PL, Harrison MR, Fox J, Parkin CA, Ingham PW, Cunliffe VT.
Baxendale S, et al. Among authors: holdsworth cj.
Dis Model Mech. 2012 Nov;5(6):773-84. doi: 10.1242/dmm.010090. Epub 2012 Jun 21.
Dis Model Mech. 2012.
PMID: 22730455
Free PMC article.
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Identification of compounds that rescue otic and myelination defects in the zebrafish adgrg6 (gpr126) mutant.
Diamantopoulou E, Baxendale S, de la Vega de León A, Asad A, Holdsworth CJ, Abbas L, Gillet VJ, Wiggin GR, Whitfield TT.
Diamantopoulou E, et al. Among authors: holdsworth cj.
Elife. 2019 Jun 10;8:e44889. doi: 10.7554/eLife.44889.
Elife. 2019.
PMID: 31180326
Free PMC article.
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Semicircular canal morphogenesis in the zebrafish inner ear requires the function of gpr126 (lauscher), an adhesion class G protein-coupled receptor gene.
Geng FS, Abbas L, Baxendale S, Holdsworth CJ, Swanson AG, Slanchev K, Hammerschmidt M, Topczewski J, Whitfield TT.
Geng FS, et al. Among authors: holdsworth cj.
Development. 2013 Nov;140(21):4362-74. doi: 10.1242/dev.098061. Epub 2013 Sep 25.
Development. 2013.
PMID: 24067352
Free PMC article.
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