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A multiorganism pipeline for antiseizure drug discovery: Identification of chlorothymol as a novel γ-aminobutyric acidergic anticonvulsant.
Jones A, Barker-Haliski M, Ilie AS, Herd MB, Baxendale S, Holdsworth CJ, Ashton JP, Placzek M, Jayasekera BAP, Cowie CJA, Lambert JJ, Trevelyan AJ, White HS, Marson AG, Cunliffe VT, Sills GJ, Morgan A. Jones A, et al. Among authors: lambert jj. Epilepsia. 2020 Oct;61(10):2106-2118. doi: 10.1111/epi.16644. Epub 2020 Aug 14. Epilepsia. 2020. PMID: 32797628 Free PMC article.
GABA-independent GABAA receptor openings maintain tonic currents.
Wlodarczyk AI, Sylantyev S, Herd MB, Kersanté F, Lambert JJ, Rusakov DA, Linthorst AC, Semyanov A, Belelli D, Pavlov I, Walker MC. Wlodarczyk AI, et al. Among authors: lambert jj. J Neurosci. 2013 Feb 27;33(9):3905-14. doi: 10.1523/JNEUROSCI.4193-12.2013. J Neurosci. 2013. PMID: 23447601 Free PMC article.
166 results