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Obsessive-compulsive disorder and attention-deficit/hyperactivity disorder: distinct associations with DNA methylation and genetic variation.
Goodman SJ, Burton CL, Butcher DT, Siu MT, Lemire M, Chater-Diehl E, Turinsky AL, Brudno M, Soreni N, Rosenberg D, Fitzgerald KD, Hanna GL, Anagnostou E, Arnold PD, Crosbie J, Schachar R, Weksberg R. Goodman SJ, et al. Among authors: lemire m. J Neurodev Disord. 2020 Aug 16;12(1):23. doi: 10.1186/s11689-020-09324-3. J Neurodev Disord. 2020. PMID: 32799817 Free PMC article.
Genome-wide association study of pediatric obsessive-compulsive traits: shared genetic risk between traits and disorder.
Burton CL, Lemire M, Xiao B, Corfield EC, Erdman L, Bralten J, Poelmans G, Yu D, Shaheen SM, Goodale T, Sinopoli VM; OCD Working Group of the Psychiatric Genomics Consortium; Soreni N, Hanna GL, Fitzgerald KD, Rosenberg D, Nestadt G, Paterson AD, Strug LJ, Schachar RJ, Crosbie J, Arnold PD. Burton CL, et al. Among authors: lemire m. Transl Psychiatry. 2021 Feb 2;11(1):91. doi: 10.1038/s41398-020-01121-9. Transl Psychiatry. 2021. PMID: 33531474 Free PMC article.
Shared genetic etiology between obsessive-compulsive disorder, obsessive-compulsive symptoms in the population, and insulin signaling.
Bralten J, Widomska J, Witte W, Yu D, Mathews CA, Scharf JM, Buitelaar J, Crosbie J, Schachar R, Arnold P, Lemire M, Burton CL, Franke B, Poelmans G. Bralten J, et al. Among authors: lemire m. Transl Psychiatry. 2020 Apr 27;10(1):121. doi: 10.1038/s41398-020-0793-y. Transl Psychiatry. 2020. PMID: 32341337 Free PMC article.
Genetic Regulation of DNA Methylation Yields Novel Discoveries in GWAS of Colorectal Cancer.
Barfield R, Huyghe JR, Lemire M, Dong X, Su YR, Brezina S, Buchanan DD, Figueiredo JC, Gallinger S, Giannakis M, Gsur A, Gunter MJ, Hampel H, Harrison TA, Hopper JL, Hudson TJ, Li CI, Moreno V, Newcomb PA, Pai RK, Pharoah PDP, Phipps AI, Qu C, Steinfelder RS, Sun W, Win AK, Zaidi SH, Campbell PT, Peters U, Hsu L. Barfield R, et al. Among authors: lemire m. Cancer Epidemiol Biomarkers Prev. 2022 May 4;31(5):1068-1076. doi: 10.1158/1055-9965.EPI-21-0724. Cancer Epidemiol Biomarkers Prev. 2022. PMID: 35247911 Free PMC article.
Genome-Wide DNA Methylation Analysis Reveals Epigenetic Dysregulation of MicroRNA-34A in TP53-Associated Cancer Susceptibility.
Samuel N, Wilson G, Lemire M, Id Said B, Lou Y, Li W, Merino D, Novokmet A, Tran J, Nichols KE, Finlay JL, Choufani S, Remke M, Ramaswamy V, Cavalli FMG, Elser C, Meister L, Taylor MD, Tabori U, Irwin M, Weksberg R, Wasserman JD, Paterson AD, Hansford JR, Achatz MIW, Hudson TJ, Malkin D. Samuel N, et al. Among authors: lemire m. J Clin Oncol. 2016 Oct 20;34(30):3697-3704. doi: 10.1200/JCO.2016.67.6940. J Clin Oncol. 2016. PMID: 27551116 Free PMC article.
Disease variants alter transcription factor levels and methylation of their binding sites.
Bonder MJ, Luijk R, Zhernakova DV, Moed M, Deelen P, Vermaat M, van Iterson M, van Dijk F, van Galen M, Bot J, Slieker RC, Jhamai PM, Verbiest M, Suchiman HE, Verkerk M, van der Breggen R, van Rooij J, Lakenberg N, Arindrarto W, Kielbasa SM, Jonkers I, van 't Hof P, Nooren I, Beekman M, Deelen J, van Heemst D, Zhernakova A, Tigchelaar EF, Swertz MA, Hofman A, Uitterlinden AG, Pool R, van Dongen J, Hottenga JJ, Stehouwer CD, van der Kallen CJ, Schalkwijk CG, van den Berg LH, van Zwet EW, Mei H, Li Y, Lemire M, Hudson TJ; BIOS Consortium; Slagboom PE, Wijmenga C, Veldink JH, van Greevenbroek MM, van Duijn CM, Boomsma DI, Isaacs A, Jansen R, van Meurs JB, 't Hoen PA, Franke L, Heijmans BT. Bonder MJ, et al. Among authors: lemire m. Nat Genet. 2017 Jan;49(1):131-138. doi: 10.1038/ng.3721. Epub 2016 Dec 5. Nat Genet. 2017. PMID: 27918535
239 results