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IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies.
Ahmad A, Pepin X, Aarons L, Wang Y, Darwich AS, Wood JM, Tannergren C, Karlsson E, Patterson C, Thörn H, Ruston L, Mattinson A, Carlert S, Berg S, Murphy D, Engman H, Laru J, Barker R, Flanagan T, Abrahamsson B, Budhdeo S, Franek F, Moir A, Hanisch G, Pathak SM, Turner D, Jamei M, Brown J, Good D, Vaidhyanathan S, Jackson C, Nicolas O, Beilles S, Nguefack JF, Louit G, Henrion L, Ollier C, Boulu L, Xu C, Heimbach T, Ren X, Lin W, Nguyen-Trung AT, Zhang J, He H, Wu F, Bolger MB, Mullin JM, van Osdol B, Szeto K, Korjamo T, Pappinen S, Tuunainen J, Zhu W, Xia B, Daublain P, Wong S, Varma MVS, Modi S, Schäfer KJ, Schmid K, Lloyd R, Patel A, Tistaert C, Bevernage J, Nguyen MA, Lindley D, Carr R, Rostami-Hodjegan A. Ahmad A, et al. Among authors: jamei m. Eur J Pharm Biopharm. 2020 Nov;156:50-63. doi: 10.1016/j.ejpb.2020.08.006. Epub 2020 Aug 14. Eur J Pharm Biopharm. 2020. PMID: 32805361
Misuse of the well-stirred model of hepatic drug clearance.
Yang J, Jamei M, Yeo KR, Rostami-Hodjegan A, Tucker GT. Yang J, et al. Among authors: jamei m. Drug Metab Dispos. 2007 Mar;35(3):501-2. doi: 10.1124/dmd.106.013359. Drug Metab Dispos. 2007. PMID: 17325025 No abstract available.
Prediction of intestinal first-pass drug metabolism.
Yang J, Jamei M, Yeo KR, Tucker GT, Rostami-Hodjegan A. Yang J, et al. Among authors: jamei m. Curr Drug Metab. 2007 Oct;8(7):676-84. doi: 10.2174/138920007782109733. Curr Drug Metab. 2007. PMID: 17979655 Review.
The Simcyp population-based ADME simulator.
Jamei M, Marciniak S, Feng K, Barnett A, Tucker G, Rostami-Hodjegan A. Jamei M, et al. Expert Opin Drug Metab Toxicol. 2009 Feb;5(2):211-23. doi: 10.1517/17425250802691074. Expert Opin Drug Metab Toxicol. 2009. PMID: 19199378 Review.
A framework for assessing inter-individual variability in pharmacokinetics using virtual human populations and integrating general knowledge of physical chemistry, biology, anatomy, physiology and genetics: A tale of 'bottom-up' vs 'top-down' recognition of covariates.
Jamei M, Dickinson GL, Rostami-Hodjegan A. Jamei M, et al. Drug Metab Pharmacokinet. 2009;24(1):53-75. doi: 10.2133/dmpk.24.53. Drug Metab Pharmacokinet. 2009. PMID: 19252336 Free article. Review.
Population-based mechanistic prediction of oral drug absorption.
Jamei M, Turner D, Yang J, Neuhoff S, Polak S, Rostami-Hodjegan A, Tucker G. Jamei M, et al. AAPS J. 2009 Jun;11(2):225-37. doi: 10.1208/s12248-009-9099-y. Epub 2009 Apr 21. AAPS J. 2009. PMID: 19381840 Free PMC article. Review.
128 results