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An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans.
Guzman MA, Rugel AR, Tarpley RS, Alwan SN, Chevalier FD, Kovalskyy DP, Cao X, Holloway SP, Anderson TJC, Taylor AB, McHardy SF, LoVerde PT. Guzman MA, et al. Among authors: alwan sn. PLoS Negl Trop Dis. 2020 Aug 18;14(8):e0008517. doi: 10.1371/journal.pntd.0008517. eCollection 2020 Aug. PLoS Negl Trop Dis. 2020. PMID: 32810153 Free PMC article.
Rational approach to drug discovery for human schistosomiasis.
LoVerde PT, Alwan SN, Taylor AB, Rhodes J, Chevalier FD, Anderson TJ, McHardy SF. LoVerde PT, et al. Among authors: alwan sn. Int J Parasitol Drugs Drug Resist. 2021 Aug;16:140-147. doi: 10.1016/j.ijpddr.2021.05.002. Epub 2021 Jun 4. Int J Parasitol Drugs Drug Resist. 2021. PMID: 34111649 Free PMC article. Review.
Corrigendum to "Rational approach to drug discovery for human schistosomiasis" [Int. J. Parasitol. Drugs Drug Resist. 16 (2021) 140-147].
LoVerde PT, Alwan SN, Taylor AB, Rhodes J, Chevalier FD, Anderson TJ, McHardy SF. LoVerde PT, et al. Among authors: alwan sn. Int J Parasitol Drugs Drug Resist. 2022 Apr;18:103. doi: 10.1016/j.ijpddr.2022.01.003. Epub 2022 Jan 19. Int J Parasitol Drugs Drug Resist. 2022. PMID: 35067439 Free PMC article. No abstract available.
Schistosome Sulfotransferases: Mode of Action, Expression and Localization.
Guzman MA, Rugel A, Alwan SN, Tarpley R, Taylor AB, Chevalier FD, Wendt GR, Collins JJ 3rd, Anderson TJC, McHardy SF, LoVerde PT. Guzman MA, et al. Among authors: alwan sn. Pharmaceutics. 2022 Jul 6;14(7):1416. doi: 10.3390/pharmaceutics14071416. Pharmaceutics. 2022. PMID: 35890311 Free PMC article.