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An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans.
Guzman MA, Rugel AR, Tarpley RS, Alwan SN, Chevalier FD, Kovalskyy DP, Cao X, Holloway SP, Anderson TJC, Taylor AB, McHardy SF, LoVerde PT. Guzman MA, et al. Among authors: chevalier fd. PLoS Negl Trop Dis. 2020 Aug 18;14(8):e0008517. doi: 10.1371/journal.pntd.0008517. eCollection 2020 Aug. PLoS Negl Trop Dis. 2020. PMID: 32810153 Free PMC article.
Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites.
Valentim CL, Cioli D, Chevalier FD, Cao X, Taylor AB, Holloway SP, Pica-Mattoccia L, Guidi A, Basso A, Tsai IJ, Berriman M, Carvalho-Queiroz C, Almeida M, Aguilar H, Frantz DE, Hart PJ, LoVerde PT, Anderson TJ. Valentim CL, et al. Among authors: chevalier fd. Science. 2013 Dec 13;342(6164):1385-9. doi: 10.1126/science.1243106. Epub 2013 Nov 21. Science. 2013. PMID: 24263136 Free PMC article.
Real-time PCR for sexing Schistosoma mansoni cercariae.
Chevalier FD, Le Clec'h W, Alves de Mattos AC, LoVerde PT, Anderson TJ. Chevalier FD, et al. Mol Biochem Parasitol. 2016 Jan-Feb;205(1-2):35-8. doi: 10.1016/j.molbiopara.2016.03.010. Epub 2016 Mar 26. Mol Biochem Parasitol. 2016. PMID: 27021570 Free PMC article.
Whole genome amplification and exome sequencing of archived schistosome miracidia.
Le Clec'h W, Chevalier FD, McDew-White M, Allan F, Webster BL, Gouvras AN, Kinunghi S, Tchuem Tchuenté LA, Garba A, Mohammed KA, Ame SM, Webster JP, Rollinson D, Emery AM, Anderson TJC. Le Clec'h W, et al. Among authors: chevalier fd. Parasitology. 2018 Nov;145(13):1739-1747. doi: 10.1017/S0031182018000811. Epub 2018 May 28. Parasitology. 2018. PMID: 29806576 Free PMC article.
Genetic Crosses and Linkage Mapping in Schistosome Parasites.
Anderson TJC, LoVerde PT, Le Clec'h W, Chevalier FD. Anderson TJC, et al. Among authors: chevalier fd. Trends Parasitol. 2018 Nov;34(11):982-996. doi: 10.1016/j.pt.2018.08.001. Epub 2018 Aug 24. Trends Parasitol. 2018. PMID: 30150002 Free PMC article. Review.
Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents.
Rugel A, Tarpley RS, Lopez A, Menard T, Guzman MA, Taylor AB, Cao X, Kovalskyy D, Chevalier FD, Anderson TJC, Hart PJ, LoVerde PT, McHardy SF. Rugel A, et al. Among authors: chevalier fd. ACS Med Chem Lett. 2018 Sep 14;9(10):967-973. doi: 10.1021/acsmedchemlett.8b00257. eCollection 2018 Oct 11. ACS Med Chem Lett. 2018. PMID: 30344901 Free PMC article.
41 results