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Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.
Schulte-Schrepping J, Reusch N, Paclik D, Baßler K, Schlickeiser S, Zhang B, Krämer B, Krammer T, Brumhard S, Bonaguro L, De Domenico E, Wendisch D, Grasshoff M, Kapellos TS, Beckstette M, Pecht T, Saglam A, Dietrich O, Mei HE, Schulz AR, Conrad C, Kunkel D, Vafadarnejad E, Xu CJ, Horne A, Herbert M, Drews A, Thibeault C, Pfeiffer M, Hippenstiel S, Hocke A, Müller-Redetzky H, Heim KM, Machleidt F, Uhrig A, Bosquillon de Jarcy L, Jürgens L, Stegemann M, Glösenkamp CR, Volk HD, Goffinet C, Landthaler M, Wyler E, Georg P, Schneider M, Dang-Heine C, Neuwinger N, Kappert K, Tauber R, Corman V, Raabe J, Kaiser KM, Vinh MT, Rieke G, Meisel C, Ulas T, Becker M, Geffers R, Witzenrath M, Drosten C, Suttorp N, von Kalle C, Kurth F, Händler K, Schultze JL, Aschenbrenner AC, Li Y, Nattermann J, Sawitzki B, Saliba AE, Sander LE; Deutsche COVID-19 OMICS Initiative (DeCOI). Schulte-Schrepping J, et al. Among authors: aschenbrenner ac. Cell. 2020 Sep 17;182(6):1419-1440.e23. doi: 10.1016/j.cell.2020.08.001. Epub 2020 Aug 5. Cell. 2020. PMID: 32810438 Free PMC article.
FOXO-dependent regulation of innate immune homeostasis.
Becker T, Loch G, Beyer M, Zinke I, Aschenbrenner AC, Carrera P, Inhester T, Schultze JL, Hoch M. Becker T, et al. Among authors: aschenbrenner ac. Nature. 2010 Jan 21;463(7279):369-73. doi: 10.1038/nature08698. Nature. 2010. PMID: 20090753
New "programmers" in tissue macrophage activation.
Aschenbrenner AC, Schultze JL. Aschenbrenner AC, et al. Pflugers Arch. 2017 Apr;469(3-4):375-383. doi: 10.1007/s00424-017-1943-9. Epub 2017 Feb 9. Pflugers Arch. 2017. PMID: 28185067 Review.
Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2.
Sander J, Schmidt SV, Cirovic B, McGovern N, Papantonopoulou O, Hardt AL, Aschenbrenner AC, Kreer C, Quast T, Xu AM, Schmidleithner LM, Theis H, Thi Huong LD, Sumatoh HRB, Lauterbach MAR, Schulte-Schrepping J, Günther P, Xue J, Baßler K, Ulas T, Klee K, Katzmarski N, Herresthal S, Krebs W, Martin B, Latz E, Händler K, Kraut M, Kolanus W, Beyer M, Falk CS, Wiegmann B, Burgdorf S, Melosh NA, Newell EW, Ginhoux F, Schlitzer A, Schultze JL. Sander J, et al. Among authors: aschenbrenner ac. Immunity. 2017 Dec 19;47(6):1051-1066.e12. doi: 10.1016/j.immuni.2017.11.024. Immunity. 2017. PMID: 29262348 Free PMC article.
Systems immunology allows a new view on human dendritic cells.
Schultze JL, Aschenbrenner AC. Schultze JL, et al. Among authors: aschenbrenner ac. Semin Cell Dev Biol. 2019 Feb;86:15-23. doi: 10.1016/j.semcdb.2018.02.017. Epub 2018 Feb 24. Semin Cell Dev Biol. 2019. PMID: 29448068 Review.
Dysregulated Functions of Lung Macrophage Populations in COPD.
Kapellos TS, Bassler K, Aschenbrenner AC, Fujii W, Schultze JL. Kapellos TS, et al. Among authors: aschenbrenner ac. J Immunol Res. 2018 Feb 18;2018:2349045. doi: 10.1155/2018/2349045. eCollection 2018. J Immunol Res. 2018. PMID: 29670919 Free PMC article. Review.
The Myeloid Cell Compartment-Cell by Cell.
Bassler K, Schulte-Schrepping J, Warnat-Herresthal S, Aschenbrenner AC, Schultze JL. Bassler K, et al. Among authors: aschenbrenner ac. Annu Rev Immunol. 2019 Apr 26;37:269-293. doi: 10.1146/annurev-immunol-042718-041728. Epub 2019 Jan 16. Annu Rev Immunol. 2019. PMID: 30649988 Review.
Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.
Bernardes JP, Mishra N, Tran F, Bahmer T, Best L, Blase JI, Bordoni D, Franzenburg J, Geisen U, Josephs-Spaulding J, Köhler P, Künstner A, Rosati E, Aschenbrenner AC, Bacher P, Baran N, Boysen T, Brandt B, Bruse N, Dörr J, Dräger A, Elke G, Ellinghaus D, Fischer J, Forster M, Franke A, Franzenburg S, Frey N, Friedrichs A, Fuß J, Glück A, Hamm J, Hinrichsen F, Hoeppner MP, Imm S, Junker R, Kaiser S, Kan YH, Knoll R, Lange C, Laue G, Lier C, Lindner M, Marinos G, Markewitz R, Nattermann J, Noth R, Pickkers P, Rabe KF, Renz A, Röcken C, Rupp J, Schaffarzyk A, Scheffold A, Schulte-Schrepping J, Schunk D, Skowasch D, Ulas T, Wandinger KP, Wittig M, Zimmermann J, Busch H, Hoyer BF, Kaleta C, Heyckendorf J, Kox M, Rybniker J, Schreiber S, Schultze JL, Rosenstiel P; HCA Lung Biological Network; Deutsche COVID-19 Omics Initiative (DeCOI). Bernardes JP, et al. Among authors: aschenbrenner ac. Immunity. 2020 Dec 15;53(6):1296-1314.e9. doi: 10.1016/j.immuni.2020.11.017. Epub 2020 Nov 26. Immunity. 2020. PMID: 33296687 Free PMC article.
47 results