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An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles.
Madsen TD, Hansen LH, Hintze J, Ye Z, Jebari S, Andersen DB, Joshi HJ, Ju T, Goetze JP, Martin C, Rosenkilde MM, Holst JJ, Kuhre RE, Goth CK, Vakhrushev SY, Schjoldager KT. Madsen TD, et al. Among authors: rosenkilde mm. Nat Commun. 2020 Aug 20;11(1):4033. doi: 10.1038/s41467-020-17473-1. Nat Commun. 2020. PMID: 32820167 Free PMC article.
2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans.
Hansen KB, Rosenkilde MM, Knop FK, Wellner N, Diep TA, Rehfeld JF, Andersen UB, Holst JJ, Hansen HS. Hansen KB, et al. Among authors: rosenkilde mm. J Clin Endocrinol Metab. 2011 Sep;96(9):E1409-17. doi: 10.1210/jc.2011-0647. Epub 2011 Jul 21. J Clin Endocrinol Metab. 2011. PMID: 21778222
Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain.
Ugleholdt R, Pedersen J, Bassi MR, Füchtbauer EM, Jørgensen SM, Kissow HL, Nytofte N, Poulsen SS, Rosenkilde MM, Seino Y, Thams P, Holst PJ, Holst JJ. Ugleholdt R, et al. Among authors: rosenkilde mm. J Biol Chem. 2011 Dec 30;286(52):44632-45. doi: 10.1074/jbc.M111.311779. Epub 2011 Oct 25. J Biol Chem. 2011. PMID: 22027838 Free PMC article.
GPR119 as a fat sensor.
Hansen HS, Rosenkilde MM, Holst JJ, Schwartz TW. Hansen HS, et al. Among authors: rosenkilde mm. Trends Pharmacol Sci. 2012 Jul;33(7):374-81. doi: 10.1016/j.tips.2012.03.014. Epub 2012 May 2. Trends Pharmacol Sci. 2012. PMID: 22560300 Review.
286 results