Vrettos EI - Search Results

1

Enhancement of glioblastoma multiforme therapy through a novel Quercetin-Losartan hybrid.

Tsiailanis AD, Renziehausen A, Kiriakidi S, Vrettos EI, Markopoulos GS, Sayyad N, Hirmiz B, Aguilar MI, Del Borgo MP, Kolettas E, Widdop RE, Mavromoustakos T, Crook T, Syed N, Tzakos AG. Tsiailanis AD, et al. Among authors: vrettos ei. Free Radic Biol Med. 2020 Nov 20;160:391-402. doi: 10.1016/j.freeradbiomed.2020.08.007. Epub 2020 Aug 18. Free Radic Biol Med. 2020. PMID: 32822744

2

Construction of Peptide-Drug Conjugates for Selective Targeting of Malignant Tumor Cells.

Vrettos EI, Tzakos AG. Vrettos EI, et al. Methods Mol Biol. 2021;2207:327-338. doi: 10.1007/978-1-0716-0920-0_23. Methods Mol Biol. 2021. PMID: 33113145

3

Rational design and structure-activity relationship studies of quercetin-amino acid hybrids targeting the anti-apoptotic protein Bcl-xL.

Kellici TF, Chatziathanasiadou MV, Lee MS, Sayyad N, Geromichalou EG, Vrettos EI, Tsiailanis AD, Chi SW, Geromichalos GD, Mavromoustakos T, Tzakos AG. Kellici TF, et al. Among authors: vrettos ei. Org Biomol Chem. 2017 Sep 26;15(37):7956-7976. doi: 10.1039/c7ob02045g. Org Biomol Chem. 2017. PMID: 28902204

4

Amplifying and broadening the cytotoxic profile of quercetin in cancer cell lines through bioconjugation.

Chatziathanasiadou MV, Geromichalou EG, Sayyad N, Vrettos EI, Katsikoudi A, Stylos E, Bellou S, Geromichalos GD, Tzakos AG. Chatziathanasiadou MV, et al. Among authors: vrettos ei. Amino Acids. 2018 Feb;50(2):279-291. doi: 10.1007/s00726-017-2514-2. Epub 2017 Nov 28. Amino Acids. 2018. PMID: 29185031

5

Development of programmable gemcitabine-GnRH pro-drugs bearing linker controllable "click" oxime bond tethers and preclinical evaluation against prostate cancer.

Vrettos EI, Karampelas T, Sayyad N, Kougioumtzi A, Syed N, Crook T, Murphy C, Tamvakopoulos C, Tzakos AG. Vrettos EI, et al. Eur J Med Chem. 2021 Feb 5;211:113018. doi: 10.1016/j.ejmech.2020.113018. Epub 2020 Nov 12. Eur J Med Chem. 2021. PMID: 33223264

6

Development of a DHA-Losartan hybrid as a potent inhibitor of multiple pathway-induced platelet aggregation.

Tsiailanis AD, Vrettos EI, Choleva M, Kiriakidi S, Ganai AM, Patha TK, Karpoormath R, Mavromoustakos T, Fragopoulou E, Tzakos AG. Tsiailanis AD, et al. Among authors: vrettos ei. J Biomol Struct Dyn. 2022;40(24):13889-13900. doi: 10.1080/07391102.2021.1996461. Epub 2021 Nov 18. J Biomol Struct Dyn. 2022. PMID: 34791990

7

On the design principles of peptide-drug conjugates for targeted drug delivery to the malignant tumor site.

Vrettos EI, Mező G, Tzakos AG. Vrettos EI, et al. Beilstein J Org Chem. 2018 Apr 26;14:930-954. doi: 10.3762/bjoc.14.80. eCollection 2018. Beilstein J Org Chem. 2018. PMID: 29765474 Free PMC article. Review.

8

Probing the interaction of a quercetin bioconjugate with Bcl-2 in living human cancer cells with in-cell NMR spectroscopy.

Primikyri A, Sayyad N, Quilici G, Vrettos EI, Lim K, Chi SW, Musco G, Gerothanassis IP, Tzakos AG. Primikyri A, et al. Among authors: vrettos ei. FEBS Lett. 2018 Oct;592(20):3367-3379. doi: 10.1002/1873-3468.13250. Epub 2018 Sep 29. FEBS Lett. 2018. PMID: 30207377 Free article.

9

Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity.

Vrettos EI, Valverde IE, Mascarin A, Pallier PN, Cerofolini L, Fragai M, Parigi G, Hirmiz B, Bekas N, Grob NM, Stylos EΚ, Shaye H, Del Borgo M, Aguilar MI, Magnani F, Syed N, Crook T, Waqif E, Ghazaly E, Cherezov V, Widdop RE, Luchinat C, Michael-Titus AT, Mindt TL, Tzakos AG. Vrettos EI, et al. Chemistry. 2020 Aug 21;26(47):10690-10694. doi: 10.1002/chem.202000924. Epub 2020 Jul 21. Chemistry. 2020. PMID: 32691857

10

Design Principles Governing the Development of Theranostic Anticancer Agents and Their Nanoformulations with Photoacoustic Properties.

Kyrkou SG, Vrettos EI, Gorpas D, Crook T, Syed N, Tzakos AG. Kyrkou SG, et al. Among authors: vrettos ei. Pharmaceutics. 2022 Feb 4;14(2):362. doi: 10.3390/pharmaceutics14020362. Pharmaceutics. 2022. PMID: 35214094 Free PMC article. Review.

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