Gillent E - Search Results

1

(-)-N-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-N-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes.

Cuypers ML, Chanteux H, Gillent E, Bonnaillie P, Saunders K, Beckers C, Delatour C, Dell'Aiera S, Ungell AL, Nicolaï J. Cuypers ML, et al. Among authors: gillent e. Drug Metab Dispos. 2020 Nov;48(11):1121-1128. doi: 10.1124/dmd.120.000089. Epub 2020 Aug 24. Drug Metab Dispos. 2020. PMID: 32839278

2

Application of Azamulin to Determine the Contribution of CYP3A4/5 to Drug Metabolic Clearance Using Human Hepatocytes.

Chanteux H, Rosa M, Delatour C, Nicolaï J, Gillent E, Dell'Aiera S, Ungell AL. Chanteux H, et al. Among authors: gillent e. Drug Metab Dispos. 2020 Sep;48(9):778-787. doi: 10.1124/dmd.120.000017. Epub 2020 Jun 12. Drug Metab Dispos. 2020. PMID: 32532738

3

Impact of In Vitro Passive Permeability in a P-gp-transfected LLC-PK1 Model on the Prediction of the Rat and Human Unbound Brain-to-Plasma Concentration Ratio.

Nicolaï J, Chapy H, Gillent E, Saunders K, Ungell AL, Nicolas JM, Chanteux H. Nicolaï J, et al. Among authors: gillent e. Pharm Res. 2020 Aug 27;37(9):175. doi: 10.1007/s11095-020-02867-z. Pharm Res. 2020. PMID: 32856111

4

Drug clearance by aldehyde oxidase: can we avoid clinical failure?

Toselli F, Golding M, Nicolaï J, Gillent E, Chanteux H. Toselli F, et al. Among authors: gillent e. Xenobiotica. 2022 Aug;52(8):890-903. doi: 10.1080/00498254.2022.2129519. Xenobiotica. 2022. PMID: 36170034

5

Role of P-glycoprotein in the brain disposition of seletalisib: Evaluation of the potential for drug-drug interactions.

Nicolas JM, Chanteux H, Nicolaï J, Brouta F, Viot D, Rosseels ML, Gillent E, Bonnaillie P, Mathy FX, Long J, Helmer E. Nicolas JM, et al. Among authors: gillent e. Eur J Pharm Sci. 2020 Jan 15;142:105122. doi: 10.1016/j.ejps.2019.105122. Epub 2019 Oct 31. Eur J Pharm Sci. 2020. PMID: 31678424

6

Use of a physiologically based pharmacokinetic-pharmacodynamic model for initial dose prediction and escalation during a paediatric clinical trial.

Johnson TN, Abduljalil K, Nicolas JM, Muglia P, Chanteux H, Nicolai J, Gillent E, Cornet M, Sciberras D. Johnson TN, et al. Among authors: gillent e. Br J Clin Pharmacol. 2021 Mar;87(3):1378-1389. doi: 10.1111/bcp.14528. Epub 2020 Sep 6. Br J Clin Pharmacol. 2021. PMID: 32822519 Free article.

7

Monitoring of a progressive functional dopaminergic deficit in the A53T-AAV synuclein rats by combining 6-[¹⁸F]fluoro-L-m-tyrosine imaging and motor performances analysis.

Becker G, Michel A, Bahri MA, Mairet-Coello G, Lemaire C, Deprez T, Freyssin A, Jacquin L, Hustadt F, De Wolf C, Caruso M, Frequin JM, Gillent E, Bezard E, Garraux G, Luxen A, Citron M, Downey P, Plenevaux A. Becker G, et al. Among authors: gillent e. Neurobiol Aging. 2021 Nov;107:142-152. doi: 10.1016/j.neurobiolaging.2021.07.012. Epub 2021 Jul 24. Neurobiol Aging. 2021. PMID: 34433125

8

Setup of human liver-chips integrating 3D models, microwells and a standardized microfluidic platform as proof-of-concept study to support drug evaluation.

Cox B, Barton P, Class R, Coxhead H, Delatour C, Gillent E, Henshall J, Isin EM, King L, Valentin JP. Cox B, et al. Among authors: gillent e. Biomater Biosyst. 2022 May 30;7:100054. doi: 10.1016/j.bbiosy.2022.100054. eCollection 2022 Aug. Biomater Biosyst. 2022. PMID: 36824483 Free PMC article.

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