Nakaoka HJ - Search Results

1

Nf1-Mutant Tumors Undergo Transcriptome and Kinome Remodeling after Inhibition of either mTOR or MEK.

Pucciarelli D, Angus SP, Huang B, Zhang C, Nakaoka HJ, Krishnamurthi G, Bandyopadhyay S, Clapp DW, Shannon K, Johnson GL, Nakamura JL. Pucciarelli D, et al. Among authors: nakaoka hj. Mol Cancer Ther. 2020 Nov;19(11):2382-2395. doi: 10.1158/1535-7163.MCT-19-1017. Epub 2020 Aug 26. Mol Cancer Ther. 2020. PMID: 32847978 Free PMC article.

2

Primary and metastatic tumors exhibit systems-level differences in dependence on mitochondrial respiratory function.

Bennett NK, Nakaoka HJ, Laurent D, Okimoto RA, Sei Y, Horvai AE, Bivona TG, Ten Hoeve J, Graeber TG, Nakamura K, Nakamura JL. Bennett NK, et al. Among authors: nakaoka hj. PLoS Biol. 2022 Sep 22;20(9):e3001753. doi: 10.1371/journal.pbio.3001753. eCollection 2022 Sep. PLoS Biol. 2022. PMID: 36137002 Free PMC article.

3

Defining the ATPome reveals cross-optimization of metabolic pathways.

Bennett NK, Nguyen MK, Darch MA, Nakaoka HJ, Cousineau D, Ten Hoeve J, Graeber TG, Schuelke M, Maltepe E, Kampmann M, Mendelsohn BA, Nakamura JL, Nakamura K. Bennett NK, et al. Among authors: nakaoka hj. Nat Commun. 2020 Aug 28;11(1):4319. doi: 10.1038/s41467-020-18084-6. Nat Commun. 2020. PMID: 32859923 Free PMC article.

4

Loss of YAP1 defines neuroendocrine differentiation of lung tumors.

Ito T, Matsubara D, Tanaka I, Makiya K, Tanei ZI, Kumagai Y, Shiu SJ, Nakaoka HJ, Ishikawa S, Isagawa T, Morikawa T, Shinozaki-Ushiku A, Goto Y, Nakano T, Tsuchiya T, Tsubochi H, Komura D, Aburatani H, Dobashi Y, Nakajima J, Endo S, Fukayama M, Sekido Y, Niki T, Murakami Y. Ito T, et al. Among authors: nakaoka hj. Cancer Sci. 2016 Oct;107(10):1527-1538. doi: 10.1111/cas.13013. Epub 2016 Sep 9. Cancer Sci. 2016. PMID: 27418196 Free PMC article.

5

Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction.

Han H, Qi R, Zhou JJ, Ta AP, Yang B, Nakaoka HJ, Seo G, Guan KL, Luo R, Wang W. Han H, et al. Among authors: nakaoka hj. Mol Cell. 2018 Oct 18;72(2):328-340.e8. doi: 10.1016/j.molcel.2018.08.038. Epub 2018 Oct 4. Mol Cell. 2018. PMID: 30293781 Free PMC article.

6

The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1.

Han H, Nakaoka HJ, Hofmann L, Zhou JJ, Yu C, Zeng L, Nan J, Seo G, Vargas RE, Yang B, Qi R, Bardwell L, Fishman DA, Cho KWY, Huang L, Luo R, Warrior R, Wang W. Han H, et al. Among authors: nakaoka hj. Nat Cell Biol. 2022 Jan;24(1):74-87. doi: 10.1038/s41556-021-00813-8. Epub 2022 Jan 13. Nat Cell Biol. 2022. PMID: 35027733 Free PMC article.

7

Mint3-mediated L1CAM expression in fibroblasts promotes cancer cell proliferation via integrin α5β1 and tumour growth.

Nakaoka HJ, Tanei Z, Hara T, Weng JS, Kanamori A, Hayashi T, Sato H, Orimo A, Otsuji K, Tada K, Morikawa T, Sasaki T, Fukayama M, Seiki M, Murakami Y, Sakamoto T. Nakaoka HJ, et al. Oncogenesis. 2017 May 15;6(5):e334. doi: 10.1038/oncsis.2017.27. Oncogenesis. 2017. PMID: 28504692 Free PMC article.

8

Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes.

Hara T, Nakaoka HJ, Hayashi T, Mimura K, Hoshino D, Inoue M, Nagamura F, Murakami Y, Seiki M, Sakamoto T. Hara T, et al. Among authors: nakaoka hj. Proc Natl Acad Sci U S A. 2017 May 30;114(22):E4416-E4424. doi: 10.1073/pnas.1703171114. Epub 2017 May 15. Proc Natl Acad Sci U S A. 2017. PMID: 28507122 Free PMC article.

9

The ERK signaling target RNF126 regulates anoikis resistance in cancer cells by changing the mitochondrial metabolic flux.

Yoshino S, Hara T, Nakaoka HJ, Kanamori A, Murakami Y, Seiki M, Sakamoto T. Yoshino S, et al. Among authors: nakaoka hj. Cell Discov. 2016 Jul 26;2:16019. doi: 10.1038/celldisc.2016.19. eCollection 2016. Cell Discov. 2016. PMID: 27462466 Free PMC article.

10

Mint3/Apba3 depletion ameliorates severe murine influenza pneumonia and macrophage cytokine production in response to the influenza virus.

Uematsu T, Fujita T, Nakaoka HJ, Hara T, Kobayashi N, Murakami Y, Seiki M, Sakamoto T. Uematsu T, et al. Among authors: nakaoka hj. Sci Rep. 2016 Nov 24;6:37815. doi: 10.1038/srep37815. Sci Rep. 2016. PMID: 27883071 Free PMC article.

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