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Sensitive detection of pre-existing BCR-ABL kinase domain mutations in CD34+ cells of newly diagnosed chronic-phase chronic myeloid leukemia patients is associated with imatinib resistance: implications in the post-imatinib era.
Iqbal Z, Aleem A, Iqbal M, Naqvi MI, Gill A, Taj AS, Qayyum A, ur-Rehman N, Khalid AM, Shah IH, Khalid M, Haq R, Khan M, Baig SM, Jamil A, Abbas MN, Absar M, Mahmood A, Rasool M, Akhtar T. Iqbal Z, et al. Among authors: akhtar t. PLoS One. 2013;8(2):e55717. doi: 10.1371/journal.pone.0055717. Epub 2013 Feb 8. PLoS One. 2013. Retraction in: PLoS One. 2024 Apr 3;19(4):e0301946. doi: 10.1371/journal.pone.0301946 PMID: 23409026 Free PMC article. Retracted.
Presence of novel compound BCR-ABL mutations in late chronic and advanced phase imatinib sensitive CML patients indicates their possible role in CML progression.
Akram AM, Iqbal Z, Akhtar T, Khalid AM, Sabar MF, Qazi MH, Aziz Z, Sajid N, Aleem A, Rasool M, Asif M, Aloraibi S, Aljamaan K, Iqbal M. Akram AM, et al. Among authors: akhtar t. Cancer Biol Ther. 2017 Apr 3;18(4):214-221. doi: 10.1080/15384047.2017.1294289. Epub 2017 Feb 21. Cancer Biol Ther. 2017. PMID: 28278078 Free PMC article.
Discovery and Protein Modeling Studies of Novel Compound Mutations Causing Resistance to Multiple Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia.
Iqbal Z, Absar M, Mahmood A, Aleem A, Iqbal M, Jameel A, Akhtar T, Karim S, Rasool M, Mirza Z, Khalid M, Akram AM, Sabar MF, Khalid AM, Aljarrah K, Iqbal J, Khalid M, Shah IH, Alanazi N. Iqbal Z, et al. Among authors: akhtar t. Asian Pac J Cancer Prev. 2020 Dec 1;21(12):3517-3526. doi: 10.31557/APJCP.2020.21.12.3517. Asian Pac J Cancer Prev. 2020. PMID: 33369447 Free PMC article.
Prognostically significant fusion oncogenes in Pakistani patients with adult acute lymphoblastic leukemia and their association with disease biology and outcome.
Sabir N, Iqbal Z, Aleem A, Awan T, Naeem T, Asad S, Tahir AH, Absar M, Hasanato RM, Basit S, Chishti MA, Faiyaz Ul-Haque M, Khalid AM, Sabar MF, Rasool M, Karim S, Khan M, Samreen B, Akram AM, Siddiqi MH, Shahzadi S, Shahbaz S, Ali AS, Mahmood A, Akram M, Saeed T, Saleem A, Mohsin D, Shah IH, Khalid M, Asif M, Iqbal M, Akhtar T. Sabir N, et al. Among authors: akhtar t. Asian Pac J Cancer Prev. 2012;13(7):3349-55. doi: 10.7314/apjcp.2012.13.7.3349. Asian Pac J Cancer Prev. 2012. PMID: 22994759 Free article.
Five most common prognostically important fusion oncogenes are detected in the majority of Pakistani pediatric acute lymphoblastic leukemia patients and are strongly associated with disease biology and treatment outcome.
Awan T, Iqbal Z, Aleem A, Sabir N, Absar M, Rasool M, Tahir AH, Basit S, Khalid AM, Sabar MF, Asad S, Ali AS, Mahmood A, Akram M, Saeed T, Saleem A, Mohsin D, Shah IH, Khalid M, Asif M, Haq R, Iqbal M, Akhtar T. Awan T, et al. Among authors: akhtar t. Asian Pac J Cancer Prev. 2012;13(11):5469-75. doi: 10.7314/apjcp.2012.13.11.5469. Asian Pac J Cancer Prev. 2012. PMID: 23317202 Free article.
High frequency and poor prognosis of late childhood BCR-ABL-positive and MLL-AF4-positive ALL define the need for advanced molecular diagnostics and improved therapeutic strategies in pediatric B-ALL in Pakistan.
Iqbal Z, Akhtar T, Awan T, Aleem A, Sabir N, Rasool M, Absar M, Akram AM, Shammas MA, Shah IH, Khalid M, Taj AS, Jameel A, Alanazi A, Gill AT, Hashmi JA, Hussain A, Sabar MF, Khalid AM, Qazi MH, Karim S, Siddiqi MH, Mahmood A, Iqbal M, Saeed A, Irfan MI. Iqbal Z, et al. Among authors: akhtar t. Mol Diagn Ther. 2015 Oct;19(5):277-87. doi: 10.1007/s40291-015-0149-0. Mol Diagn Ther. 2015. PMID: 26266519
Integrated Genomic Analysis Identifies ANKRD36 Gene as a Novel and Common Biomarker of Disease Progression in Chronic Myeloid Leukemia.
Iqbal Z, Absar M, Akhtar T, Aleem A, Jameel A, Basit S, Ullah A, Afzal S, Ramzan K, Rasool M, Karim S, Mirza Z, Iqbal M, AlMajed M, AlShehab B, AlMukhaylid S, AlMutairi N, Al-Anazi N, Sabar MF, Arshad M, Asif M, Shammas M, Mahmood A. Iqbal Z, et al. Among authors: akhtar t. Biology (Basel). 2021 Nov 15;10(11):1182. doi: 10.3390/biology10111182. Biology (Basel). 2021. PMID: 34827175 Free PMC article.
293 results