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Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial.
Olivotto I, Oreziak A, Barriales-Villa R, Abraham TP, Masri A, Garcia-Pavia P, Saberi S, Lakdawala NK, Wheeler MT, Owens A, Kubanek M, Wojakowski W, Jensen MK, Gimeno-Blanes J, Afshar K, Myers J, Hegde SM, Solomon SD, Sehnert AJ, Zhang D, Li W, Bhattacharya M, Edelberg JM, Waldman CB, Lester SJ, Wang A, Ho CY, Jacoby D; EXPLORER-HCM study investigators. Olivotto I, et al. Among authors: afshar k. Lancet. 2020 Sep 12;396(10253):759-769. doi: 10.1016/S0140-6736(20)31792-X. Epub 2020 Aug 29. Lancet. 2020. PMID: 32871100 Clinical Trial.
Microvascular Loss and Diastolic Dysfunction in Severe Symptomatic Cardiac Allograft Vasculopathy.
Daud A, Xu D, Revelo MP, Shah Z, Drakos SG, Dranow E, Stoddard G, Kfoury AG, Hammond MEH, Nativi-Nicolau J, Alharethi R, Miller DV, Gilbert EM, Wever-Pinzon O, McKellar SH, Afshar K, Khan F, Fang JC, Selzman CH, Stehlik J. Daud A, et al. Among authors: afshar k. Circ Heart Fail. 2018 Aug;11(8):e004759. doi: 10.1161/CIRCHEARTFAILURE.117.004759. Circ Heart Fail. 2018. PMID: 30354559
Mixed cellular and antibody-mediated rejection in heart transplantation: In-depth pathologic and clinical observations.
Kfoury AG, Miller DV, Snow GL, Afshar K, Stehlik J, Drakos SG, Budge D, Fang JC, Revelo MP, Alharethi RA, Gilbert EM, Caine WT, McKellar S, Molina KM, Hammond MEH. Kfoury AG, et al. Among authors: afshar k. J Heart Lung Transplant. 2016 Mar;35(3):335-341. doi: 10.1016/j.healun.2015.10.016. Epub 2015 Oct 23. J Heart Lung Transplant. 2016. PMID: 26586489
Integrated multiomic analysis identifies TRIP13 as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis.
St Pierre L, Berhan A, Sung EK, Alvarez JR, Wang H, Ji Y, Liu Y, Yu H, Meier A, Afshar K, Golts EM, Lin GY, Castaldi A, Calvert BA, Ryan A, Zhou B, Offringa IA, Marconett CN, Borok Z. St Pierre L, et al. Among authors: afshar k. Biochim Biophys Acta Mol Basis Dis. 2024 Nov 13:167572. doi: 10.1016/j.bbadis.2024.167572. Online ahead of print. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 39547519
198 results