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Page 1
Trappc9 deficiency causes parent-of-origin dependent microcephaly and obesity.
Liang ZS, Cimino I, Yalcin B, Raghupathy N, Vancollie VE, Ibarra-Soria X, Firth HV, Rimmington D, Farooqi IS, Lelliott CJ, Munger SC, O'Rahilly S, Ferguson-Smith AC, Coll AP, Logan DW. Liang ZS, et al. Among authors: rimmington d. PLoS Genet. 2020 Sep 2;16(9):e1008916. doi: 10.1371/journal.pgen.1008916. eCollection 2020 Sep. PLoS Genet. 2020. PMID: 32877400 Free PMC article.
The effects of neurokinin B upon gonadotrophin release in male rodents.
Corander MP, Challis BG, Thompson EL, Jovanovic Z, Loraine Tung YC, Rimmington D, Huhtaniemi IT, Murphy KG, Topaloglu AK, Yeo GS, O'Rahilly S, Dhillo WS, Semple RK, Coll AP. Corander MP, et al. Among authors: rimmington d. J Neuroendocrinol. 2010 Mar;22(3):181-7. doi: 10.1111/j.1365-2826.2009.01951.x. Epub 2009 Dec 23. J Neuroendocrinol. 2010. PMID: 20041982
Adult onset global loss of the fto gene alters body composition and metabolism in the mouse.
McMurray F, Church CD, Larder R, Nicholson G, Wells S, Teboul L, Tung YC, Rimmington D, Bosch F, Jimenez V, Yeo GS, O'Rahilly S, Ashcroft FM, Coll AP, Cox RD. McMurray F, et al. Among authors: rimmington d. PLoS Genet. 2013;9(1):e1003166. doi: 10.1371/journal.pgen.1003166. Epub 2013 Jan 3. PLoS Genet. 2013. PMID: 23300482 Free PMC article.
Role for the obesity-related FTO gene in the cellular sensing of amino acids.
Gulati P, Cheung MK, Antrobus R, Church CD, Harding HP, Tung YC, Rimmington D, Ma M, Ron D, Lehner PJ, Ashcroft FM, Cox RD, Coll AP, O'Rahilly S, Yeo GS. Gulati P, et al. Among authors: rimmington d. Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):2557-62. doi: 10.1073/pnas.1222796110. Epub 2013 Jan 28. Proc Natl Acad Sci U S A. 2013. PMID: 23359686 Free PMC article.
Insulin-like peptide 5 is an orexigenic gastrointestinal hormone.
Grosse J, Heffron H, Burling K, Akhter Hossain M, Habib AM, Rogers GJ, Richards P, Larder R, Rimmington D, Adriaenssens AA, Parton L, Powell J, Binda M, Colledge WH, Doran J, Toyoda Y, Wade JD, Aparicio S, Carlton MB, Coll AP, Reimann F, O'Rahilly S, Gribble FM. Grosse J, et al. Among authors: rimmington d. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11133-8. doi: 10.1073/pnas.1411413111. Epub 2014 Jul 15. Proc Natl Acad Sci U S A. 2014. PMID: 25028498 Free PMC article. Clinical Trial.
FTO is necessary for the induction of leptin resistance by high-fat feeding.
Tung YC, Gulati P, Liu CH, Rimmington D, Dennis R, Ma M, Saudek V, O'Rahilly S, Coll AP, Yeo GS. Tung YC, et al. Among authors: rimmington d. Mol Metab. 2015 Feb 7;4(4):287-98. doi: 10.1016/j.molmet.2015.01.011. eCollection 2015 Apr. Mol Metab. 2015. PMID: 25830092 Free PMC article.
Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity.
Dalgaard K, Landgraf K, Heyne S, Lempradl A, Longinotto J, Gossens K, Ruf M, Orthofer M, Strogantsev R, Selvaraj M, Lu TT, Casas E, Teperino R, Surani MA, Zvetkova I, Rimmington D, Tung YC, Lam B, Larder R, Yeo GS, O'Rahilly S, Vavouri T, Whitelaw E, Penninger JM, Jenuwein T, Cheung CL, Ferguson-Smith AC, Coll AP, Körner A, Pospisilik JA. Dalgaard K, et al. Among authors: rimmington d. Cell. 2016 Jan 28;164(3):353-64. doi: 10.1016/j.cell.2015.12.025. Cell. 2016. PMID: 26824653 Free PMC article.
Loss of Mrap2 is associated with Sim1 deficiency and increased circulating cholesterol.
Novoselova TV, Larder R, Rimmington D, Lelliott C, Wynn EH, Gorrigan RJ, Tate PH, Guasti L; Sanger Mouse Genetics Project; O'Rahilly S, Clark AJ, Logan DW, Coll AP, Chan LF. Novoselova TV, et al. Among authors: rimmington d. J Endocrinol. 2016 Jul;230(1):13-26. doi: 10.1530/JOE-16-0057. Epub 2016 Apr 22. J Endocrinol. 2016. PMID: 27106110 Free PMC article.
30 results