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Page 1
Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane.
Van QN, López CA, Tonelli M, Taylor T, Niu B, Stanley CB, Bhowmik D, Tran TH, Frank PH, Messing S, Alexander P, Scott D, Ye X, Drew M, Chertov O, Lösche M, Ramanathan A, Gross ML, Hengartner NW, Westler WM, Markley JL, Simanshu DK, Nissley DV, Gillette WK, Esposito D, McCormick F, Gnanakaran S, Heinrich F, Stephen AG. Van QN, et al. Among authors: frank ph. Proc Natl Acad Sci U S A. 2020 Sep 29;117(39):24258-24268. doi: 10.1073/pnas.2006504117. Epub 2020 Sep 10. Proc Natl Acad Sci U S A. 2020. PMID: 32913056 Free PMC article.
Evaluation of macrocyclic Grb2 SH2 domain-binding peptide mimetics prepared by ring-closing metathesis of C-terminal allylglycines with an N-terminal beta-vinyl-substituted phosphotyrosyl mimetic.
Oishi S, Karki RG, Shi ZD, Worthy KM, Bindu L, Chertov O, Esposito D, Frank P, Gillette WK, Maderia M, Hartley J, Nicklaus MC, Barchi JJ Jr, Fisher RJ, Burke TR Jr. Oishi S, et al. Bioorg Med Chem. 2005 Apr 1;13(7):2431-8. doi: 10.1016/j.bmc.2005.01.052. Bioorg Med Chem. 2005. PMID: 15755645
Gateway cloning is compatible with protein secretion from Pichia pastoris.
Esposito D, Gillette WK, Miller DA, Taylor TE, Frank PH, Hu R, Bekisz J, Hernandez J, Cregg JM, Zoon KC, Hartley JL. Esposito D, et al. Among authors: frank ph. Protein Expr Purif. 2005 Apr;40(2):424-8. doi: 10.1016/j.pep.2004.12.006. Protein Expr Purif. 2005. PMID: 15766886 Free PMC article.
Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical studies of prenylated protein-lipid interactions.
Gillette WK, Esposito D, Abreu Blanco M, Alexander P, Bindu L, Bittner C, Chertov O, Frank PH, Grose C, Jones JE, Meng Z, Perkins S, Van Q, Ghirlando R, Fivash M, Nissley DV, McCormick F, Holderfield M, Stephen AG. Gillette WK, et al. Among authors: frank ph. Sci Rep. 2015 Nov 2;5:15916. doi: 10.1038/srep15916. Sci Rep. 2015. PMID: 26522388 Free PMC article.
Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ.
Dharmaiah S, Bindu L, Tran TH, Gillette WK, Frank PH, Ghirlando R, Nissley DV, Esposito D, McCormick F, Stephen AG, Simanshu DK. Dharmaiah S, et al. Among authors: frank ph. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6766-E6775. doi: 10.1073/pnas.1615316113. Epub 2016 Oct 17. Proc Natl Acad Sci U S A. 2016. PMID: 27791178 Free PMC article.
Optimizing high-yield production of SARS-CoV-2 soluble spike trimers for serology assays.
Esposito D, Mehalko J, Drew M, Snead K, Wall V, Taylor T, Frank P, Denson JP, Hong M, Gulten G, Sadtler K, Messing S, Gillette W. Esposito D, et al. bioRxiv [Preprint]. 2020 May 28:2020.05.27.120204. doi: 10.1101/2020.05.27.120204. bioRxiv. 2020. Update in: Protein Expr Purif. 2020 Oct;174:105686. doi: 10.1016/j.pep.2020.105686 PMID: 32511418 Free PMC article. Updated. Preprint.
Standardization of enzyme-linked immunosorbent assays for serosurveys of the SARS-CoV-2 pandemic using clinical and at-home blood sampling.
Klumpp-Thomas C, Kalish H, Drew M, Hunsberger S, Snead K, Fay MP, Mehalko J, Shunmugavel A, Wall V, Frank P, Denson JP, Hong M, Gulten G, Messing S, Hicks J, Michael S, Gillette W, Hall MD, Memoli M, Esposito D, Sadtler K. Klumpp-Thomas C, et al. medRxiv [Preprint]. 2020 May 25:2020.05.21.20109280. doi: 10.1101/2020.05.21.20109280. medRxiv. 2020. Update in: Nat Commun. 2021 Jan 4;12(1):113. doi: 10.1038/s41467-020-20383-x PMID: 32511472 Free PMC article. Updated. Preprint.
37 results