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Elucidating the gut microbiota composition and the bioactivity of immunostimulatory commensals for the optimization of immune checkpoint inhibitors.
Daillère R, Routy B, Goubet AG, Cogdill A, Ferrere G, Alves-Costa Silva C, Fluckiger A, Ly P, Haddad Y, Pizzato E, Thelemaque C, Fidelle M, Mazzenga M, Roberti MP, Melenotte C, Liu P, Terrisse S, Kepp O, Kroemer G, Zitvogel L, Derosa L. Daillère R, et al. Among authors: liu p. Oncoimmunology. 2020 Jul 20;9(1):1794423. doi: 10.1080/2162402X.2020.1794423. Oncoimmunology. 2020. PMID: 32934888 Free PMC article. Review.
The oncolytic peptide LTX-315 triggers necrotic cell death.
Forveille S, Zhou H, Sauvat A, Bezu L, Müller K, Liu P, Zitvogel L, Pierron G, Rekdal Ø, Kepp O, Kroemer G. Forveille S, et al. Among authors: liu p. Cell Cycle. 2015;14(21):3506-12. doi: 10.1080/15384101.2015.1093710. Cell Cycle. 2015. PMID: 26566869 Free PMC article.
The oncolytic compound LTX-401 targets the Golgi apparatus.
Zhou H, Sauvat A, Gomes-da-Silva LC, Durand S, Forveille S, Iribarren K, Yamazaki T, Souquere S, Bezu L, Müller K, Leduc M, Liu P, Zhao L, Marabelle A, Zitvogel L, Rekdal Ø, Kepp O, Kroemer G. Zhou H, et al. Among authors: liu p. Cell Death Differ. 2016 Dec;23(12):2031-2041. doi: 10.1038/cdd.2016.86. Epub 2016 Sep 2. Cell Death Differ. 2016. PMID: 27588704 Free PMC article.
Identification of pharmacological agents that induce HMGB1 release.
Liu P, Zhao L, Loos F, Iribarren K, Lachkar S, Zhou H, Gomes-da-Silva LC, Chen G, Bezu L, Boncompain G, Perez F, Zitvogel L, Kepp O, Kroemer G. Liu P, et al. Sci Rep. 2017 Nov 2;7(1):14915. doi: 10.1038/s41598-017-14848-1. Sci Rep. 2017. PMID: 29097772 Free PMC article.
eIF2α phosphorylation is pathognomonic for immunogenic cell death.
Bezu L, Sauvat A, Humeau J, Gomes-da-Silva LC, Iribarren K, Forveille S, Garcia P, Zhao L, Liu P, Zitvogel L, Senovilla L, Kepp O, Kroemer G. Bezu L, et al. Among authors: liu p. Cell Death Differ. 2018 Aug;25(8):1375-1393. doi: 10.1038/s41418-017-0044-9. Epub 2018 Jan 22. Cell Death Differ. 2018. PMID: 29358668 Free PMC article.
Photodynamic therapy with redaporfin targets the endoplasmic reticulum and Golgi apparatus.
Gomes-da-Silva LC, Zhao L, Bezu L, Zhou H, Sauvat A, Liu P, Durand S, Leduc M, Souquere S, Loos F, Mondragón L, Sveinbjørnsson B, Rekdal Ø, Boncompain G, Perez F, Arnaut LG, Kepp O, Kroemer G. Gomes-da-Silva LC, et al. Among authors: liu p. EMBO J. 2018 Jul 2;37(13):e98354. doi: 10.15252/embj.201798354. Epub 2018 May 28. EMBO J. 2018. PMID: 29807932 Free PMC article.
Epigenetic anticancer agents cause HMGB1 release in vivo.
Liu P, Zhao L, Loos F, Iribarren K, Kepp O, Kroemer G. Liu P, et al. Oncoimmunology. 2018 Feb 14;7(6):e1431090. doi: 10.1080/2162402X.2018.1431090. eCollection 2018. Oncoimmunology. 2018. PMID: 29872561 Free PMC article.
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