van Meer P - Search Results

1

Animal-free applications in the development of cell-based therapies.

van Meer P, Theunissen P, van den Hoorn T, Herberts C, van der Laan JW. van Meer P, et al. Br J Clin Pharmacol. 2021 Jun;87(6):2425-2427. doi: 10.1111/bcp.14544. Epub 2020 Sep 15. Br J Clin Pharmacol. 2021. PMID: 32935350 Free article. No abstract available.

2

The value of non-human primates in the development of monoclonal antibodies.

van Meer PJ, Kooijman M, van der Laan JW, Moors EH, Schellekens H. van Meer PJ, et al. Among authors: van der laan jw. Nat Biotechnol. 2013 Oct;31(10):882-3. doi: 10.1038/nbt.2709. Nat Biotechnol. 2013. PMID: 24104750 No abstract available.

3

Applicability of organ-on-chip systems in toxicology and pharmacology.

Schneider MR, Oelgeschlaeger M, Burgdorf T, van Meer P, Theunissen P, Kienhuis AS, Piersma AH, Vandebriel RJ. Schneider MR, et al. Among authors: van meer p. Crit Rev Toxicol. 2021 Jul;51(6):540-554. doi: 10.1080/10408444.2021.1953439. Epub 2021 Aug 31. Crit Rev Toxicol. 2021. PMID: 34463591

4

A roadmap towards a human-centric safety assessment of advanced therapy medicinal products.

Chien HT, de Leeuw VC, van Esterik JCJ, Russel FGM, Kienhuis AS, Theunissen PT, van Meer P. Chien HT, et al. Among authors: van meer p. Regul Toxicol Pharmacol. 2024 Jun;150:105631. doi: 10.1016/j.yrtph.2024.105631. Epub 2024 Apr 20. Regul Toxicol Pharmacol. 2024. PMID: 38648873 Free article.

5

The use of weight-of-evidence approaches to characterize developmental toxicity risk for therapeutic monoclonal antibodies in humans without in vivo studies.

Chien HT, Roos P, Russel FGM, Theunissen PT, van Meer PJK. Chien HT, et al. Among authors: van meer pjk. Regul Toxicol Pharmacol. 2024 Sep;152:105682. doi: 10.1016/j.yrtph.2024.105682. Epub 2024 Jul 31. Regul Toxicol Pharmacol. 2024. PMID: 39094967 Free article.

6

Evaluation of rat and rabbit embryofetal development studies with pharmaceuticals: the added value of a second species.

Roos P, Anggasta C, Piersma AH, van Meer PJK, Theunissen PT. Roos P, et al. Among authors: van meer pjk. Crit Rev Toxicol. 2024 Oct;54(9):619-633. doi: 10.1080/10408444.2024.2374281. Epub 2024 Aug 2. Crit Rev Toxicol. 2024. PMID: 39093553 Review.

7

The safety, efficacy and regulatory triangle in drug development: Impact for animal models and the use of animals.

van Meer PJ, Graham ML, Schuurman HJ. van Meer PJ, et al. Eur J Pharmacol. 2015 Jul 15;759:3-13. doi: 10.1016/j.ejphar.2015.02.055. Epub 2015 Mar 27. Eur J Pharmacol. 2015. PMID: 25818943 Review.

8

Are some animal models more equal than others? A case study on the translational value of animal models of efficacy for Alzheimer's disease.

Veening-Griffioen DH, Ferreira GS, van Meer PJK, Boon WPC, Gispen-de Wied CC, Moors EHM, Schellekens H. Veening-Griffioen DH, et al. Among authors: van meer pjk. Eur J Pharmacol. 2019 Sep 15;859:172524. doi: 10.1016/j.ejphar.2019.172524. Epub 2019 Jul 7. Eur J Pharmacol. 2019. PMID: 31291566 Free article.

9

Comparison of drug efficacy in two animal models of type 2 diabetes: A systematic review and meta-analysis.

Ferreira GS, Veening-Griffioen DH, Boon WPC, Hooijmans CR, Moors EHM, Schellekens H, van Meer PJK. Ferreira GS, et al. Among authors: van meer pjk. Eur J Pharmacol. 2020 Jul 15;879:173153. doi: 10.1016/j.ejphar.2020.173153. Epub 2020 Apr 28. Eur J Pharmacol. 2020. PMID: 32360835 Free article.

10

A standardised framework to identify optimal animal models for efficacy assessment in drug development.

Ferreira GS, Veening-Griffioen DH, Boon WPC, Moors EHM, Gispen-de Wied CC, Schellekens H, van Meer PJK. Ferreira GS, et al. Among authors: van meer pjk. PLoS One. 2019 Jun 13;14(6):e0218014. doi: 10.1371/journal.pone.0218014. eCollection 2019. PLoS One. 2019. PMID: 31194784 Free PMC article.

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